Lipids - Synthesis/Metabolism

Question 1

for VLDL, what is the
- site of synthesis
- major function
- major apolipoprotein
- residence time in plasma

Answer 1

• site of synthesis: liver
• major function: transport endogenous cholesterol and TG
• major apolipoprotein: B100, E, CI/II/III
• residence time in plasma: 15-30min

Question 2

how does the major role of VLDL differ in fed vs. fasted state

Answer 2

fasted: transports endogenous cholesterol + TG

fed: transports endogenous cholesterol + dietary fats

Question 3

for IDL, what is the
- site of synthesis
- major function
- major apolipoprotein
- residence time in plasma

Answer 3

• site of synthesis:
• major function:
• major apolipoprotein:
• residence time in plasma:

Question 4

for LDL, what is the
- site of synthesis
- major function
- major apolipoprotein
- residence time in plasma

Answer 4

• site of synthesis:
• major function:
• major apolipoprotein:
• residence time in plasma:

Question 5

for HDL, what is the
- site of synthesis
- major function
- major apolipoprotein
- residence time in plasma

Answer 5

• site of synthesis:
• major function:
• major apolipoprotein:
• residence time in plasma:

Question 6

for chylomicrons, what is the
- site of synthesis
- major function
- major apolipoprotein
- residence time in plasma

Answer 6

• site of synthesis:
• major function:
• major apolipoprotein:
• residence time in plasma:

Question 7

for chylomicron remnants, what is the
- site of synthesis
- major function
- major apolipoprotein
- residence time in plasma

Answer 7

• site of synthesis:
• major function:
• major apolipoprotein:
• residence time in plasma: