Linezolid Flashcards
1
Q
What is the MOA of linezolid?
A
- Active against gram +ve bacteria
- Bacteriostatic
- Narrow spec
2
Q
Indication
A
- Complicated skin + tissue infections
- Pneumonia
- MRSA (used as an alternative)
3
Q
Side effect
A
Blood disorders: Monitor: FBC (esp Tx >10-14 days, severe RI, drugs)
Optic neuropathy
- Monitor: visual functions >28 days
- Counsel: report visual impairment, visual defects, eyesight changes
4
Q
Interaction
A
INC hypertensive crises
- Tyramine rich food
- MAOI (wait 2 weeks)
- Beta2 agonists
- Sympathomimetics (adrenaline)
