lecture 2 - Immune cells and organs

Question 1

what is a primary lymphoid organ

Answer 1

this is where lymphocytes are produced via lymphopoiesis.

Question 2

what is a secondary lymphoid organ ? and give three examples

Answer 2

where lymphocytes can interact with antigen and with other lymphocytes

spleen
lymph nodes
mucosal associated lymphoid tissues (MALT)

Question 3

what is MALT

Answer 3

mucosal associated lymphoid tissues - a diffuse system of small concentrations of lymphoid tissue found in various submucosal membrane sites of the body, such as the gastrointestinal tract, thyroid, breast, lung, salivary glands, eye, and skin.

Question 4

what do Hassall’s corpuscle

do ?

Answer 4

these contain fibreblasts which secrete soluble factors essential for the development of regulatory t lymphocytes

Question 5

what do chemokines do ?

Answer 5

these are small soluble molecules specific to particular lymphocytes and guide these lymphocytes to different positions within lymph nodes