lecture 18 Flashcards
why is regeneration risky
cancer
why is it hard to trigger regeneration
cell diff. is a one way trip
totipotent
cell has every single possibility
totipotent human cel
oocyte
totipotent organism
planaria
planaria mechaisms
can loose fully differentiated cells by eating to stay alive
planarai stem cell
neoblast; totpotent
whoc an do limited regeneration
amphibians (limb/tail)
what helps w that
blatema; stem cells are forming and doing regeneration
how do amphibians regenerate
pluripotent cells, form blatema upon woudning, regenerate missing limb
what can humans do
embryonic stem cells (hella renegrative potential)
what creates stem cell
Kif 4, Oct4, Sox2
what do they do
differentated cell to induced pluripotent stem cell
what do they cause
upregulation of stem cell promoting proteins ,downreg. of proteins for regeneration
