Lecture 15 - Population Genetics and Risk Analysis Flashcards

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1
Q

The logarithm of the odds of linkage is also known as the:

A

lod score

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2
Q

What 5 factors throw a population out of HWE?

A
  1. Non-random mating
  2. Small population size
  3. Migration (gene flow)
  4. Mutation
  5. Selection
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3
Q

What are the 3 types of non-random mating?

A
  1. Inbreeding
  2. Assortative Mating
  3. Population Stratification
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4
Q

Consanguineous marriages increase the expression of:

A

rare autosomal recessive diseases

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5
Q

Which type of non-random mating is defined as “mating based on a particular phenotype”?

A

Assortative mating

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6
Q

Which type of non-random mating is defined as “an artifact that occurs when the breeding population is not defined accurately”?

A

population stratification

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