Lecture 10

Question 1

What are the 5 classes of antibodies?

Answer 1

IgM, IgG, IgA, IgD, IgE

Question 2

What is the largest class of antibody?

Answer 2

IgM

Question 3

What class of antibody is produced first and why?

Answer 3

IgM as it has the ability to bind 10 individual antigens greatly improving the efficiency of phagocytosis through agglugation

Question 4

What antibody class is predominately used as defense system of mucous membranes?

Answer 4

IgA

Question 5

What antibody class is transported across the placenta?

Answer 5

IgG

Question 6

What is the most abundant antibody class?

Answer 6

IgG

Question 7

What antibody class is found on virgin B lymphocytes?

Answer 7

IgD

Question 8

What antibody is used to deal with parasites?

Answer 8

IgE

Question 9

What membrane proteins are found on both helper T cells and killer T cells?

Answer 9

TCR and CD3

Question 10

What membrane proteins can be used to distinguish Helper T cells from cytotoxic T cells?

Answer 10

CD8 found on Killer T cells, CD4 found on helper T cells

Question 11

What is the function of the TCR protein?

Answer 11

Receptors for antigens bound by the MHC proteins on cells

Question 12

What are the class one MHCs?

Answer 12

HLA-A/B/C

Question 13

What are the class two MHCs?

Answer 13

HLA-DP/DQ/DR

Question 14

What is the difference between class one and two MHCs?

Answer 14

Class one is on every nucleated cell and Class two is only found on antigen presenting cells

Question 15

Which MHC class do helper T cells react with?

Answer 15

Class two

Question 16

What MHC class do cytotoxic T cells react with?

Answer 16

Class one

Question 17

What is the difference between antigen processing with the two classes of MHC?

Answer 17

Class one is typically from infectious processes While Class two is from phagocytosed invaders

Question 18

What happens when a cytotoxic T cell is activated?

Answer 18

It proliferates into more cytotoxic T cells and memory cells