Lecture 1

Question 1

Protein can change shape by:

Answer 1

Charge distribution, Covalent bonding (phosphorylation), Allosteric binding

Question 2

Where solutes go…..

Answer 2

Water follows…

Question 3

Transporter Protein Channels open with:

Answer 3

Interaction w/binding site causes protein to change shape; gate is closed and then once solute binds to proteins, opens with the ligand binding or voltage change.

Question 4

Pore or leak channels are open:

Answer 4

All the time

Question 5

Which ions tend to run INTO cells?

Answer 5

Sodium, Calcium, Chloride, Bicarb, Glucose

Question 6

Which ions tend to run OUT of cells?

Answer 6

Potassium, Magnesium, Phosphorous, AA, ATP

Question 7

Steps in phagocytosis:

Answer 7

Bacteria / foreign debris fuse internally with phagosome –> Lysosome (enzymatic breakdown

Question 8

Receptor Mediated Endocytosis:

Answer 8

Cytoplasmic protein goes to plasma membrane –> ligand receptors gather in clathrin-coated pit –> invaginates and pinches off vesicle capturing large quantities of ligand –> Clathrin coat lost –> Recycling of receptors to plasma membrane

Question 9

100% of the plasma membrane is internalized in ______________

Answer 9

1 hour