Lactate Flashcards

1
Q

Acid

A

Compound that donates H+

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2
Q

Base

A

Compound that gives up OH

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3
Q

Resting muscle and Blood pH

A

Muscle- 6.9-7.1
Blood- 7.4 (to regulate cellular acidity)

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4
Q

Formula for lactate

A

C3H5O3
- does not diffuse into blood for buffering
Cannot give up H+

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5
Q

Does Lactate cause muscle acidosis?

A

NO
- Actually does the opposite as it consumes an H+
NADH H+ ↓ NAD+

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6
Q

Lactate Shuttle

A

MCT1 shuttle
- Lactate can be transported between muscles or organs to be used as fuel)

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7
Q

Where does lactate go?

A

1) TO muscles, tissues
2) Excreted through sweat and urination
3) TO liver to be converted into glucose

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8
Q

Blood lactate levels correlate to?

A

H+ levels
Acidification of blood and muscles

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9
Q

Blood lactate threshold

A

The point of %VO2 (exercise intensity) that lactate increases rapidly
50% in untrained
75% in trained

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10
Q

Where does H+ come from in anaerobic exercise

A

1) Intermediary steps of glycolysis
2) Hydrolysis of ATP

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11
Q

How does high intensity exercise affect pH

A

An increase in H+ and decrease in pH
Muscle- lowest recorded was 6.4
Blood- around 7

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12
Q

A decrease in pH relates to

A

A decrease in muscular force production

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13
Q

Buffering capacity

A

Ability to resist change in muscle pH
Highest in sprinters
Lower in marathon runners (do not reach lactate threshold)

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