L6 complex traits

Question 1

how do you detect linkage between genes?

Answer 1

a deviation from expectations based on mendels principle of independence (overrepresented progeny of parents types)

Question 2

when there is variation in progeny from purebred lines, this is most likely due to what?

Answer 2

uncontrolled environmental variation

Question 3

what the complex traits?

Answer 3

those with more than 2 genes, up to those controlled by the joint actions of 100s or 1000s of genes

Question 4

what is the formula for H^2? broad sense heritability

Answer 4

Vg/Vt=Vg/(Vg+Ve)

Question 5

what does heritability depend on?

Answer 5

the environment

Question 6

what is concordance?

Answer 6

the fraction of pairs of that both have condition, given that one has condition

Question 7

what are QTL studies?
what does it test for?

Answer 7

a measurement of phenotypic differences between two differentiated lineages

tests for associations between loci and differentiated traits in the F2 progeny