L:30 Metabolism Flashcards

1
Q

Important precursor to all nucleotides

A

(PRPP) 5-Phospho-a;pha-D-ribosyl-1-pyrophosphate

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2
Q

Pyrimidines form nitrogenous base ______ of PRPP

A

independent

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3
Q

de novo synthesis is a ______ pathway

A

Unidirectional

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4
Q

Precursors used in de novo synthesis of ribonucleotides

A

NH3 from Gln
Asp
HCO3

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5
Q

Allosteric regulation of synthesis

A

Pyrimidines inhibits Cytosine

Purines activates A/G

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