L 22 CNS Stimulants Flashcards by Mac Mac | Brainscape

Q

“Psychomotor” stimulants MOA?

A

indirect-acting (presynaptic) sympathomimetics

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Q

Stimulants that serve as Transporter Substrates?

A

(release catecholamines)

amphetamine

dextrose-amphetamine

ephedrine

methamphetamine

methylphenidate

pemoline

pseudoephedrine

tyramine

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Q

Non selective transporter inhibitors?

A

cocaine

sibutramine

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Q

Atypical transporter inhibitors?

A

modafinil

bupropion

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Q

Modafinil MOA?

A

effects diff than cocaine

may bind to another site on DAT & SERT

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Q

Bupropion MOA?

A

blocks reuptake of both NE & DA

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Q

Selective reuptake inhibitors/ blockers for NET?

A

atomoxetine

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Q

Atomoxetine MOA?

A

selective NE uptake inhibitor

1st non stimulant for ADHD

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Q

Non Psychomotor stimulants?

A

Methylxanthines:

caffeine

theophylline – tea

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Q

Non Psychomotor stimulants MOA?

A

Adenosine antagonists

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Q

Misc. Stimulants drugs?

A

Pargyline (MOA -)

Entacapone (COMT -)

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Q

Amphetamine SE?

A

Inc systolic & diastolic Pressure

HR reflexively DEC

Arrythmias

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Q

CNS SE of stimulants?

A

wakefulness

alertness

elevation of mood

elation/ euphoria

Inc motor/ speech

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Q

Contraindications?

A

anorexia

insomnia

asthenia

psychopathic personality
hx of homicidal or suicidal

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