introduction

Question 1

colonisation

Answer 1

the presence of a microbe in the human body without an inflammatory response

Question 2

infection

Answer 2

inflammation due to a microbe

Question 3

bacteraemia

Answer 3

the presence of viable bacteria in the blood

Question 4

sepsis

Answer 4

the dysregulated host response to infection - new definition of sepsis

Question 5

technical sepsis defition

Answer 5

life-threatening organ dysfunction caused by a dysregulated host response to infection

Question 6

septic shock

Answer 6

is a subset of sepsis with circulatory and cellular/metabolic dysfunction associated with a higher risk of mortality

Question 7

Sepsis 6 bundle

Answer 7

SIRS has superseded

and different criteria used now

Question 8

SIRS

Answer 8

mislabelling because so overly sensitive, more antibiotics used instead

Question 9

SOFA

Answer 9

Sequential Organ function Assessment Score:

respirtation 
coagulation 
Liver 
cvd 
Central nervous system: glasgow coma scale 
Renal

Question 10

qSOFA

Answer 10

quick sofa assessment:
RR >22bpm
sBP <100mmHg
Altered GCS

Screening for outcome rather than diagnosis

0 = mortality <1% 
1 = mortality 2-3% 
>=2 = Mortality >=10%

Question 11

with SIRS:

Answer 11

removal of severe sepsis

only simple infection, sepsis and septic shock

Question 12

sepsis with SIRS:

Answer 12

infection and organ failure (may include hypotension, hyperlactaemia or vasopressors)

Question 13

septic shock with SIRS

Answer 13

attempt of resuscitation has been made