Introduction

Question 1

What is the average length of a mentrual cycle?

Answer 1

28-35 days

Question 2

What are the 2 types of cycles?

Answer 2

Ovarian
Uterine

Question 3

What happens in the ovarian cycle:
day 1-13
day 14
day 15-28

Answer 3

Follicular (follicular genesis and maturation)

Ovulation (follicle then released)

Luteal phase (follicle accumulates fatty deposits + cholesterol which becomes corpus luteum)

Question 4

What does the corpus luteum secrete a lot of?

Answer 4

Progesterone

Question 5

What happens in the uterine cycle:
Day 1-5
Day 6-14
Day 15-28

Answer 5

Menses = low oestrogen and progesterone

Proliferative = High oestrogen (build up the endometrium)

Secretory (lots of mucus production) = high progesterone (maintains endometrium, habitable for implantation)

Question 6

What happens on day 12-13 and why?

Answer 6

LH surge
36 hours pre ovulation drives up oestrogen

Question 7

What is a marker test for ovulation?
when should it be done?

Answer 7

mid luteal progesterone
(cycle length - 7 days)
eg. measure on day 21 as 28-7=21

Question 8

What does oestrogen do to the body?

Answer 8

female body composition

good for bone mineral density BMD

lots of spiral arterioles (more blood
blow to uterus)

builds up endometrium

Question 9

What does progesterone do?

Answer 9

increase uterine mucus secretion

maintains endometrium

smooth muscle relaxation (myometrium)

Question 10

What does LH act on to produce?

Answer 10

acts on THECA cells to produce oestrogen

Question 11

What does FSH act on and key for?

Answer 11

acts on GRANULOSA cells, key for follicular genesis

Question 12

When does the LH surge only happen?

Answer 12

When isolated high oestrogen
(oestrogen + progesterone high = -ve feedback)