Impulse Control Flashcards

1
Q

What changes occurred in Phineas Gage after his accident?

A

He returned to full health apart from personality changes, including being fitful, irreverent, profane, and impatient of restraint or advice.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Who is credited with the birth of psychosurgery, and what was a common procedure?

A

Antonio Egas Moniz. Lobotomies were common but often had varied and crude outcomes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What drug marked the end of lobotomies for mental illness treatment?

A

The antipsychotic Thorazine.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the role of the frontal cortex, according to Robert Sapolsky?

A

It helps choose the harder but better option when faced with a choice.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the Iowa Gambling Task?

A

A task where participants choose from four decks of cards, with two offering short-term gain and long-term loss (non-advantageous) and two offering short-term loss and long-term gain (advantageous).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the three characteristics of addiction?

A
  1. Compulsive drug seeking and taking.
  2. Inability to stop and high relapse rates after cessation.
  3. Drugs become more wanted but less liked over time
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What percentage of people who try illicit drugs develop an addiction?

A

Approximately 5-10%.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the meso-limbic dopamine system?

A

A key brain system involved in reward and pleasure.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How does long-term drug use affect the brain?

A

It leads to structural changes in the brain, such as reduced cortical gray matter volume and changes in dendritic spines, which can increase impulsive behavior.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How does impulsivity relate to drug addiction?

A

Long-term drug use may increase impulsivity, and pre-existing impulsive traits may increase the risk of drug use.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the prefrontal model of addiction?

A

The prefrontal cortex is involved in impulsive decision-making and inhibitory control. Drugs cause long-lasting changes in brain regions, leading to increased impulsivity and risk-taking behavior.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What was observed in PET scans of cocaine users?

A

Reduced orbitofrontal cortex (OFC) function during protracted withdrawal compared to control subjects.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is delay discounting, and how is it affected in methamphetamine users?

A

Delay discounting is the preference for smaller, immediate rewards over larger, delayed rewards. Methamphetamine users more quickly choose the smaller-immediate reward.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How has the number of mental disorders in the DSM evolved over time?

A

From 108 in the first edition (1952) to 354 in DSM-IV (1994). The DSM-5 adjusted criteria rather than significantly changing the number of disorders.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What issue has arisen with the expansion of the DSM?

A

Diagnostic inflation, potentially increasing diagnoses by up to 28%.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How do ethical limitations affect drug research?

A

Ethical limitations, especially with drug-naive subjects, complicate establishing causality in drug research.

17
Q

What method is used to study drug self-administration in animals?

A

Intravenous drug self-administration.

18
Q

What are the main findings about the prefrontal cortex and addiction?

A
  1. The prefrontal cortex is involved in impulsive decision-making and temporal discounting.
  2. Drugs cause long-term changes in motivation, emotion, and decision-making areas.
  3. These changes increase impulsive behavior.
  4. Pre-existing impulsivity may increase drug addiction risk.