Immunisations Flashcards

1
Q

acquired immunity increases in __+__ with each exposure

A

strength and effectiveness

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2
Q

vaccine type that stimulates B, Th and TK cells

A

live attenuated - most effective

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3
Q

examples of live attenuated vaccines

A
BCG
. MMR
. Oral polio vaccine
. Chicken pox (varicella)
. Influenza
. Rotavirus
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4
Q

examples of inactivated vaccines

A
Polio
. Influenza
. Hepatitis A and B
. Tetanus
. Diphtheria
. Pertussis
. HPV
. MenC
. MenACWY
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5
Q

inactivated vaccines stimulate + cells

A

B and Th

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6
Q

toxoid vaccine examples =

A

diphtheria

tetanus (DTaP)

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7
Q

toxoid vaccines stimulate __+__ cells

A

Th and B

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8
Q

R0 (basic reproductive number) =

A

average number of secondary cases due to 1 infected individual in a susceptible envnt

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9
Q

passive immunity (Ig) given if __/__

A

at risk of severe disease

if have comorbidites

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10
Q

an increased R0 means the number of the population needed to be immune for herd immunity __

A

increases too

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11
Q

organism that causes diphtheria

s+s

A

corynebacterium diphtheriae
sore throat
low grade fever
pseudomembrane

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12
Q

5 in 1 vaccine =

A
diphtheria
tetanus
pertussis 
polio
HiB
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13
Q

elimination of a disease =

A

incidence is 0 in a geoographical area - requires continued intervention

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14
Q

eradication of a disease =

A

permanent reduction of incidence to 0 worldwide - no further intervention methods required

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15
Q

bulging fontanelle =

A

meningitis

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16
Q

contraindications to getting a vaccine

A

if immunosuppressed or pregnant
previous confirmed anaphylaxis to same antigen or component
anaphylactic response to egg - yellow fever contraind, MMR safe, flu potentially safe
if acutely unwell infant (mild is ok though)

17
Q

premature babies should have their immunisations at what age?

A

chronological age irrespective of how prem they were