Hypoxic ischaemic encephalopahty

Question 1

brain damage resulting from ante- or perinatal […]

Answer 1

hypoxia

Question 2

Hypoxia –> poor O2 supply to brain cells –> irreversible brain damage (via immediate neuronal […] and delayed […] injury

Answer 2

death, reperfusion

Question 3

Categories of hypoxia
- Pre-partum (e.g., placental […])
- Intra-partum (e.g., cord […])
- Post-partum (e.g., prolonged respiratory arrest).

Answer 3

abruption
compression

Question 4

Invx
[…] monitoring and multiple MRI brain scans

Answer 4

EEG

Question 5

Mx
respiratory support, anticonvulsant therapy, careful fluid balance and electrolyte monitoring, and potentially the use of inotropes.
Mild […] can also prevent further damage by secondary […] injury

Answer 5

hypothermia, reperfusion