HY B&B REVISÃO Flashcards
Ephysema is destruction of what cells?
Type I pneumocytes (LONG AND FLAT)
EMPHYSEMA LEADS TO?
CHRONIC CO2 RETENTION -> RESPIRATORY ACIDOCIS -> INCREASES BICARB TO COMPENSATE
TYPE II PNEUMOCYTE FUNCTION
STEM CELLS OF THE LUNG - REGENERATES DAMAGED + PRODUCES SURFACTANT FROM LAMELLAR BODIES
PSEUDOSTRATIFIED COLUMNAR CELLS
PRIMARY CELL FUCKED UP IN SMOKING
ACTIVITIES OF CILIATED CELLS IN SMOKING
DECREASED
MACROPHAGES PRODUCES WHAT IN SARCOIDOSIS?
1-A HYDROXYLASE -> INCREASING 1,25 AND HYPERCALCEMIA DUE TO INCREASED BOWEL ABSORPTION
WHAT NEEDS TO BE W/ INTEGRITY TO RESTORE?
BASEMENT MEMBRANE
MACROPHAGES IN SMOKING?
DECREASED
AMOUNT OF AIR INHALED + EXHALED DURING NORMAL BREATHING
TIDAL VOLUME
MAXIMUM CAPACITY OF INSPIRATION - FORCED
INSPIRATORY CAPACITY
ADDITIONAL AMOUNT OF AIR THAT CAN BE INHALED AFTER NORMAL INSPIRATION
INSPIRATORY RESIDUAL VOLUME
MAXIMUM OF EXPIRATORY THAT CAN BE EXHALED
EXPIRATORY RESERVE VOLUME
VOLUME OF AIR THAT CONTINUOUS IN THE LUNGS AND CAN’T BE EXHALED EVEN W/ MAXIMUM EXPIRATION
RESIDUAL VOLUME
AIR IS PUXED TO A PLACE W/ HIGH OR LOW PRESSURE?
LOW
OBSTRUCTIVE DISEASE VALUES (AIR TRAPPING!!!!)
LOW FEV1/FVC RATIO (LOWS BOTH)
HIGH TOTAL LUNG CAPACITY
NORMAL TV
LOW INSPIRATORY RESERVE VOLUME
INCREASED RESIDUAL VOLUME
DECREASED EXPIRATORY RESERVE VOLUME
RESTRICTIVE DISEASES (AIR CANT GET IN!!!)
MILDLY DECREASED FEV1/FVC RATIO
DECREASED TOTAL LUNG CAPACITY
MILDLY DECREASED IN TIDAL VOLUME
DECREASED RESIDUAL VOLUME
DECREASED RECOIL
OBSTRUCTIVE HAS DECREASED RECOIL?
NO
EXAMPLES OF OBSTRUCTIVE DISEASES
ASTHMA, COPD + OLD AGE RELATED CHANGES
EXAMPLES OF RESTRICTIVE DISEASES:
PULMONARY FIBROSIS - IDIOPATHIC, RADIATION, DRUGS + PNEUMOCONIOSES
