HUP Medicine Flashcards
IBD
Anti-TNF: Adalimumab, infliximab (remicade), certolzumab
Anti-integrin: natalizumab, vedolizumab (entivio), ustekinumab
IBD
Anti-TNF
Integrin inhibitors
NSCLC:
EGFR tyrosine kinase inhibitors: erlotinib, gefitinib, afatinib
Anaplastic lymphoma kinase (ALk) critzotinib
SCLC: chemo
Lung cancer tx
NSCLC
SCLC
Mag ox 800mg to replete PO, or IV ***
Mag repletion
Fecal calprotectin
Bacteriostatic, sequesters mag and zinc, nl 50
4-factor prothrombin complex concentrate 10,9,7,2 10 Prothrombin=2 Fibrinogen=1 Novel Anticoags inhibit factor 10
https://www.google.com/search?q=coag+cascade&client=safari&hl=en-us&prmd=inmv&source=lnms&tbm=isch&sa=X&ved=0ahUKEwjF8vuI597NAhXm4IMKHT0XC70Q_AUIBygB&biw=375&bih=559#imgrc=x678-UY3cJAM8M%3A
CA-125 -ovarian
CA
C
Tumor markers
Saxagliptin
Incretin
Add on to metformin
Pancreatitis and pancreatic CA increased risk?
(Incretins as a group also not yet proven for increased)
Possible autoimmune in ddx
Pancreatitis that isn’t alcohol or gallstone
Thrombotic micros angioplasty
TTP HUS Drug-induced Etc... Also post-transplant
E.g. Calcineurin inhibitors, antibody-mediated
Claritin for bone marrow pain
Patients pain liquid tumors
Gabapentin causes twitching
Twitching: low mg, low cal
Discriminate factor high in alcoholic liver failure
pT, PT control, bilirubin
Needs steroids
Can get acute pulmonary failure
PPIs
Careful of fluid status
Absolute reticulocyte count and index–if index appropriate, shows that patients bone marrow is keeping up with making appropriate retics response for the anemia level
Sickle cell
Mag sulf: 1meq raises 0.1 points
Potassium sulf: 10meq raises 0.1 points
Mag and K repletion
Magic number of days to treat COPD with steroids: 5
5
If post c diff tx, and starting abx, continue vanc with other news to prevent recurrence of cdiff
Cdiff
