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infectious diseases > human herpes virus, AIDS, other virus infections > Flashcards

human herpes virus, AIDS, other virus infections Flashcards

1
Q

Epstein-Barr

Human herpesvirus ___
3 Types of infection

Mode of transmission?

A 
Human herpesvirus 4 (HHV-4),
Types of infection:
Infectious mononucleosis
Nasopharyngeal carcinoma
Burkitt’s lymphoma (Epstein Barr virus found in 100% of patients)
Mode of transmission: direct contact
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2
Q 
I came in to see my physician assistant because of…
Fever
Sore throat
Swollen lymph nodes
Lack of appetite
Rash
Fatigue
Weakness and sore muscles
A

EBV

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3
Q

EBV symptom course

A

incubation few weeks then fever and sore throat

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4
Q 
Physical exam findings
Think Strep throat +
Lymphadenopathy. Strep is anterior cervical, mono is Anterior posterior and cervical
Exudative pharyngitis
Enlarged spleen
A

EBV

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5
Q

lymphadenopathy

strep vs mono

A

Strep is anterior chain,

Mono is Anterior posterior and cervical

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6
Q

Heterophil antibody test ( Monospot)

Antibody test

A

EBV
Heterophil antibody test ( Monospot)
False positives and negatives may occur
Retest a few weeks later to confirm results if necessary
EBV Antibody test
The presence of EBV IgM indicates acute infection

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7
Q

EBV exam (4)

A

Think Strep throat +
Lymphadenopathy: Anterior posterior and cervical
Exudative pharyngitis
Enlarged spleen

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8
Q

EBV tests (2)

A

-Heterophil antibody test ( Monospot)
False positives and negatives may occur
Retest a few weeks later to confirm results if necessary
-EBV Antibody test
The presence of EBV IgM indicates acute infection

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9
Q

Treatment for EBV

A 
No specific treatment other than treating the symptoms
Painkillers  relieve body aches
Acetaminophen – to bring down fever
Ibuprofen
Hydration – water therapy
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10
Q

EBV CBC

A

granulocytopenia then lymphocytic leukocytosis

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11
Q

Name four disease where we might see tzanck cells

A

Herpes simplex
Varicella and herpes zoster
Pemphigus vulgaris
Cytomegalovirus

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12
Q 
Varicella Zoster 
Human herpesvirus \_\_
Primary Infection \_\_\_
Incubation period from \_\_\_ days
Infectious when?
Transmitted how?
Herpes Zoster Shingles – Recurrent Disease – about \_\_% reactivation
A

Human herpesvirus 3
Primary Infection – Chickenpox
Incubation period from 10-21 days
Infectious from a few days before rash appears until lesions are completely dry
Transmitted through droplet or direct contact with lesions
Herpes Zoster Shingles – Recurrent Disease – about 15% reactivation

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13
Q

I came in to see my physician assistant today because of…
Persistent lymphadenopathy
Fever
Night sweats
Weight loss with significant muscle wasting
N/V/D
Sore throat

A

AIDS

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14
Q 
AIDS tx(3)
and management(2)

antibodies develop when

A

Two enzyme-linked immunosorbent assays (ELISA) are performed
Western blot is performed to confirm the diagnosis
Antibodies typically develop within 6 months of exposure
Monitor CD4
Monitor viral load

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15
Q

what test confirms AIDS

A

western blot

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16
Q

Postexposure prophylaxis with antiretrovirals AIDS
Begin within __ hours and continue for at least __ weeks
Needlestick injury from known HIV positive patient has a ___% chance of causing disease

A

Begin within 72 hours and continue for at least 4 weeks

Needlestick injury from known HIV positive patient has a 0.3% chance of causing disease

17
Q

Antiretrovirals for AIDS (3)

A

Zidovudine (AZT)
Abacavir (Ziagen)
Didanosine (Videx)

18
Q

Any question referring to owl eye inclusion bodies should make you think of what disease?

A mother brings in a 3 year old boy who has had a fever and runny nose. He is feeling better, but she noticed this red lacy rash on his face and upper torso. Can he go to daycare?

A

Any question referring to owl eye inclusion bodies should make you think of what disease?CMV

A mother brings in a 3 year old boy who has had a fever and runny nose. He is feeling better, but she noticed this red lacy rash on his face and upper torso. Can he go to daycare?
Yes, if it is 5th disease he is no longer contagious

19
Q

Child presents with 4 days of of fever and two small white spots in his mouth. What might they be?

Where does the Rubeola rash begin?

A child presents with very little symptoms other than a low grade fever and a light red rash which started on his chest and has moved to his legs. What is the most likely childhood exanthem?

Why not give a pregnant woman the rubella vaccine?
It contains live virus

A

Child presents with 4 days of of fever and two small white spots in his mouth. What might they be?
Koplik’s spots – measles

Where does the Rubeola rash begin?
On the face

A child presents with very little symptoms other than a low grade fever and a light red rash which started on his chest and has moved to his legs. What is the most likely childhood exanthem?

Roseola (measles they are much much sicker)
Why not give a pregnant woman the rubella vaccine?
It contains live virus

20
Q

Parovirus B19

A

erythema infectiosum

21
Q

what worsens with fever and sun exposure

A

erythema infectiosum slapped cheek rash

22
Q

what exanthem has no prodrome

A

erythema infectiosum

23
Q

worst complication is in what exanthem

A

erythema infectiosum: aplastic crisis

24
Q

paramyxovirus

A

measles

25
Q

low fever with 3 C’s(coryza, conjunctivitis, cough)

A

measles

26
Q

Parovirus B19
paramyxovirus
HHV 6 and 7
coxsackie

A

erythema infectiosum
measles
roseola infantum
hand foot mouth disease

27
Q

koplik spots

A

measles

28
Q

rash with measles

A

erythematous maculopapular rash spreads from head to toe

29
Q

measles prodrome and rash

A
  • low fever with 3 C’s(coryza, conjunctivitis, cough)

- erythematous maculopapular rash spreads from head to toe

30
Q

3 day measles

A

rubella

31
Q

posterior auricular lymphadenopathy

A

rubella

32
Q

erythematous maculopapular rash spreads from head to toe

A

measles and rubella

33
Q

main difference between measles and rubella

A

rubella has a low grade fever and do not appear as ill

34
Q

roseola infantum virus

-describe rash

A

hhv 6 and 7
-maculopapular rash appears as fever breaks; begins on trunk and quickly spreads to the face and extremities and often last under 24 hours

35
Q

hhv 6 and 7
-maculopapular rash appears as fever breaks; begins on trunk and quickly spreads to the face and extremities and often last under 24 hours

A

roseola infantum

36
Q 
virus:
erythema infectiosum
measles
roseola infantum
hand foot mouth disease
A

Parovirus B19
paramyxovirus
HHV 6 and 7
coxsackie

infectious diseases (7 decks)

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