human herpes virus

Question 1

herpesviridae

Answer 1

1) most people carry latent ones
2) very good at creating mild disease

Question 2

HSV-1

Answer 2

1) whitlow, cold sores

Question 3

HSV-2

Answer 3

1) genital lesions
2) very painful
3) could be disseminated
- could be immunocompromised
4) differential diagnosis should include shingles

Question 4

lesion histology

Answer 4

1) full of fluid with virus

Question 5

how the virus enters

Answer 5

1) enter through epithelial tissue
2) theres more

Question 6

HHV-3

Answer 6

1) varicella zoster virus
2) not fluid filled, more like pox
3) unilateral presentation
- important diagnostic indicator for shingles
- follow dermatome
4) lives in dorsal root ganglion or enteric ganglion

Question 7

HHV-4

Answer 7

1) epstein barr virus
2) infectious mononucleosis
3) hairy leukoplakia on tongue > resides in memory B cells and epithelial tissue
- risk for neoplastic change
- high risk if lesion is red or mixed red and white

Question 8

HHV-5

Answer 8

1) cytolomegalovirus
2) look unusually shaped
- broad tropism
- thickening of epithelial tissue

Question 9

HHV-8

Answer 9

1) kaposi’s sarcoma
2) neoplasms of endothelial lining of vasculature
3) looks like bruising, purpura, can be raised and red
4) in advanced conditions of HIV, AIDS

Question 10

medication

Answer 10

1) suppress chronic outbreaks
- acyclovir
2) DNA polymerase targeting
- stop replication of viral genome
3 )prodrugs that must be processed
- so it is active only in cells where virus is present