HTN Jeopardy

Question 1

Which 2 agents should not be combined with aliskiren and describe the reason why

Answer 1

ACE-I and ARBS

because of increased risk of renal dysfunction

Question 2

Beta-blockers will cause these symptoms when the drug is started but will go away within a few weeks

Answer 2

beta-blocker blues - fatigue, tired, depression, “funny heart beat”

Question 3

terazosin causes this side effect which is why it must be taken at bedtime

Answer 3

first dose hypotension

Question 4

Which drug class do you not want to use in a patient with renal artery stenosis?

Answer 4

ACE-I

Question 5

Name 3 drugs that should be dosed in the morning

Answer 5

loops, thiazides, and potassium sparing diuretics

Question 6

propanolol acts via this specific MOA

Answer 6

blocks both beta 1 and beta 2 receptors

Question 7

this is a good agent to use in pregnancy

Answer 7

methyldopa or labetalol

Question 8

this class of medication does not inhibit the breakdown of bradykinin thus is much less likely to cause the dry cough

Answer 8

ARBs

Question 9

Metoprolol succinate is dosed how often?

Answer 9

once daily

Question 10

Rebound HTN will occur with these classes of medication if suddenly discontinued

Answer 10

beta-blockers and clonidine

Question 11

Which agent would you want to avoid in patients with high potassium?

Answer 11

potassium sparing diuretics, aldosterone antaonists, ACE-I and ARBs

Question 12

this drug class inhibits the conversion of angiotensin I to angiotensin II

Answer 12

ACE-I

Question 13

if a patient needs HTN medication, what are the 3 options for starting therapy?

Answer 13

1 - start 1 drug and max the dose
(then add a second max it out
add a third)
2 - start 1 drug and add on another prior to maxing the dose on the first drug (then max both before adding third)
3 - if SBP > 160/ DBP> 100, start 2 drugs (max those out before adding third)

Question 14

report any peripheral edema with this class of medication

Answer 14

dihydropyridines

Question 15

this is the most common side effect of captopril

Answer 15

dry cough

Question 16

use precaution with these 2 drug classes in patients with sulfa allergies

Answer 16

thiazides and loops

Question 17

Most ACE-I are dosed this way with the specific exception of this ACE-I which is dosed 2-3x per day

Answer 17

once daily,

captopril is dosed 2-3x per day

Question 18

This medication class competes with aldosterone, prevents sodium reabsorption and potassium excretion

Answer 18

aldosterone receptor blockers

Question 19

this beta-blocker can be used to prevent migraines

Answer 19

propanolol

Question 20

report any swelling of the lips, face or neck with the following 2 drug classes

Answer 20

ACE-I/ARBs

Question 21

This is the number one side effect of verapamil

Answer 21

constipation

Question 22

Which drug class do you not want to use in a patient with CHF?

Answer 22

non-dihydropyridines

Question 23

Clonidine patch is changed this often

Answer 23

every 7 days

Question 24

This medication class inhibits active transport of sodium chloride and potassium in thick ascending limb of Loop of Henle, causing excretion of these ions

Answer 24

loop diuretics

Question 25

these 2 drug classes should be avoided in African American patients

Answer 25

ACE-I/ARBs

Question 26

Describe how the electrolytes are affected by HCTZ

Answer 26

potassium and sodium decrease,

uric acid and calcium increase

Question 27

This medication prevents sodium reabsorption in the distal tubule

Answer 27

thiazide diuretics

Question 28

do not take salt substitutes with the following drug classes

Answer 28

ACE-I, ARBs and potassium sparing diuretics and aldosterone antagonists

Question 29

this drug class is typically dosed at night

Answer 29

alpha 1 blockers

Question 30

name at least 1 drug class that you should not use during pregnancy

Answer 30

ACE-I/ARBs