Hormone Receptors etc Flashcards
1
Q
Heterodimers
A
Retinoic Acid (RAR, RXR), T3/T4, Vitamin D
2
Q
Homodimers
A
Cortisol, Androgens
3
Q
Insulin
A
Tyrosine Kinase
4
Q
No intrinsic kinase activity
A
Leptin and Growth Hormone
JAK/STAT signaling
5
Q
Gs
A
Secretin, Glucagon, GIP, VIP, Beta-Adrenergic
6
Q
Gi
A
Ang II, Alpha-adrenergic
Decrease cAMP
7
Q
Gq
A
Gastrin, CCK, Ghrelin, Motilin
Acts via PLC, IP3/DAG, Ca2+
8
Q
PDE
A
Degrades cAMP
Insulin stimulates PDE
Caffeine inhibits PDE