Hormone Receptors etc Flashcards

1
Q

Heterodimers

A

Retinoic Acid (RAR, RXR), T3/T4, Vitamin D

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2
Q

Homodimers

A

Cortisol, Androgens

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3
Q

Insulin

A

Tyrosine Kinase

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4
Q

No intrinsic kinase activity

A

Leptin and Growth Hormone

JAK/STAT signaling

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5
Q

Gs

A

Secretin, Glucagon, GIP, VIP, Beta-Adrenergic

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6
Q

Gi

A

Ang II, Alpha-adrenergic

Decrease cAMP

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7
Q

Gq

A

Gastrin, CCK, Ghrelin, Motilin

Acts via PLC, IP3/DAG, Ca2+

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8
Q

PDE

A

Degrades cAMP
Insulin stimulates PDE
Caffeine inhibits PDE

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