HIV Flashcards
what are the transmission routes of HIV?
sexual intercourse
vertical (mother to baby, breastfeeding)
sharing needles
blood transfusion
organ transplant
Two types of HIV
HIV 1 and 2
HIV
Human Immunodeficiency Virus
Physiology of HIV
attaches to CD4 T cells and macrophages then integrated into DNA and moves to lymph nodes
Destroys the CD4 cells
point of care testing
blood sample taken from patients finger will reveal in 60 seconds
HIV gives you an increased risk of developing what?
infections
tumours
the lower the CD4 count the higher the?
severity of disease
infections and tumours that develop due to a weak immune system classified as what?
AIDS
if NO symptoms you have HIV
AIDS
acquired immunodeficiency syndrome
Symptoms of HIV include:
flu-like illness
fever
malaise/ lethargy
lymphadenopathy
toxic exanthema
what is a common late stage AIDS infection?
pneumocystic jiroveci pneumonia
how do you treat HIV?
combination antiretroviral therapy
cART
combination antiretroviral therapy
3 drugs from 2 different groups
how long are patients on treatment for?
life long treatment
examples of antiviral drugs
nucleoside reverse transcriptase inhibitors
non-nucleoside reverse transcriptase inhibitors
protease inhibitors
integrase inhibitors