HIV Flashcards

1
Q

what are the transmission routes of HIV?

A

sexual intercourse

vertical (mother to baby, breastfeeding)

sharing needles

blood transfusion

organ transplant

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2
Q

Two types of HIV

A

HIV 1 and 2

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3
Q

HIV

A

Human Immunodeficiency Virus

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4
Q

Physiology of HIV

A

attaches to CD4 T cells and macrophages then integrated into DNA and moves to lymph nodes

Destroys the CD4 cells

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5
Q

point of care testing

A

blood sample taken from patients finger will reveal in 60 seconds

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6
Q

HIV gives you an increased risk of developing what?

A

infections

tumours

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7
Q

the lower the CD4 count the higher the?

A

severity of disease

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8
Q

infections and tumours that develop due to a weak immune system classified as what?

A

AIDS

if NO symptoms you have HIV

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9
Q

AIDS

A

acquired immunodeficiency syndrome

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10
Q

Symptoms of HIV include:

A

flu-like illness

fever

malaise/ lethargy

lymphadenopathy

toxic exanthema

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11
Q

what is a common late stage AIDS infection?

A

pneumocystic jiroveci pneumonia

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12
Q

how do you treat HIV?

A

combination antiretroviral therapy

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13
Q

cART

A

combination antiretroviral therapy

3 drugs from 2 different groups

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14
Q

how long are patients on treatment for?

A

life long treatment

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15
Q

examples of antiviral drugs

A

nucleoside reverse transcriptase inhibitors

non-nucleoside reverse transcriptase inhibitors

protease inhibitors

integrase inhibitors

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16
Q

complications of ART:

A

lipodystrophy

rash

diarrhoea and vomiting

hepatitis

17
Q

how do you prevent HIV?

A

behaviour change and condoms

circumcision

Treatment as prevention

pre-exposure prophylaxis

post- exposure prophylaxis

18
Q

common infections people can get from HIV immunodeficiency

A

TB

EBV

HSV (herpes)

CMV (Cytomegalovirus)