Herpes Flashcards
Abbrrivation, common name, latent location of the Human Herpesvirus that causes cold sores, oral ulcers and percent of US people infected
HHV-1
Herpes simplex virus-1
Neuron
67%
Abbrrivation, common name, latent location of the Human Herpesvirus that causes Genital herpes
HHV-2
Herpes simplex Virus -2
Neuron
15%
Abbrrivation, common name, latent location of the Human Herpesvirus that causes chicken pox and shingles
HHV-3
Varicella-Zoster Virus
Neuron
100%
Abbrrivation, common name, latent location of the Human Herpesvirus that causes Infectious Mono. and Burkitt’s lymphoma
HHV-4 Epstein-Barr Virus B-Cells mono ->75% B.L.-> 50%
Abbrrivation, common name, latent location of the Human Herpesvirus that causes Congenital infection
HHV 5 Cytomegalovirus Lymph/Mono. 100% Only a problem for a fetus if mother is initially infected while pregnant
Abbrrivation, common name, latent location of the Human Herpesvirus that causes Roseola infantum (2 types)
1. HHV-6 latent in mono/macrophages 100% 2. HHV-7 latent in T cells 10% high fever in babies
Abbrrivation, common name, latent location of the Human Herpesvirus that causes Kaposi’s sarcoma
HHV-8
Kaposi’s Sarcoma Virus
Lymphocytes
Only with AIDS patients
What is unique about the Herpes virus and how it is formed?
It replicates and assembles in the nucleus then they aquire their envelope (and spikes) BEFORE they reach the cytoplasmic outer membrane. Then exocytosed from cell
Where do most antiviral therapies attack?
large dsDNA genome - can lessen viral shedding and recurrence of symptoms - none can cure latent infection