Herpes Flashcards

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1
Q

Abbrrivation, common name, latent location of the Human Herpesvirus that causes cold sores, oral ulcers and percent of US people infected

A

HHV-1
Herpes simplex virus-1
Neuron
67%

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2
Q

Abbrrivation, common name, latent location of the Human Herpesvirus that causes Genital herpes

A

HHV-2
Herpes simplex Virus -2
Neuron
15%

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3
Q

Abbrrivation, common name, latent location of the Human Herpesvirus that causes chicken pox and shingles

A

HHV-3
Varicella-Zoster Virus
Neuron
100%

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4
Q

Abbrrivation, common name, latent location of the Human Herpesvirus that causes Infectious Mono. and Burkitt’s lymphoma

A
HHV-4
Epstein-Barr Virus
B-Cells
mono ->75%
B.L.-> 50%
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5
Q

Abbrrivation, common name, latent location of the Human Herpesvirus that causes Congenital infection

A
HHV 5
Cytomegalovirus
Lymph/Mono.
100% 
Only a problem for a fetus if mother is initially infected while pregnant
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6
Q

Abbrrivation, common name, latent location of the Human Herpesvirus that causes Roseola infantum (2 types)

A
1. HHV-6
latent in mono/macrophages
100%
2. HHV-7
latent in T cells
10%
high fever in babies
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7
Q

Abbrrivation, common name, latent location of the Human Herpesvirus that causes Kaposi’s sarcoma

A

HHV-8
Kaposi’s Sarcoma Virus
Lymphocytes
Only with AIDS patients

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8
Q

What is unique about the Herpes virus and how it is formed?

A

It replicates and assembles in the nucleus then they aquire their envelope (and spikes) BEFORE they reach the cytoplasmic outer membrane. Then exocytosed from cell

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9
Q

Where do most antiviral therapies attack?

A

large dsDNA genome - can lessen viral shedding and recurrence of symptoms - none can cure latent infection

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