Heme and Oxygen Flashcards
Chemical composition of an RBC membrane:
40% lipids
-52% proteins
-8% carbohydrates
RBC membrane contains approximately
0% proteins and carbohydrates
Two of the most important protein constituents of the RBC membrane
glycophorin, an integral membrane protein, and spectrin, a peripheral membrane protein
gives the erythrocytes their negative charge.
sialic acid
anion-exchange channel glycoprotein
transport proteins
receptors
glycophorins
are relevant foreign substances capable of inducing an immune reaction.
antigens
The synthesis of hemogloin relies on 3 stages:
- Iron delivery
- Protoporphryn synthesis
- Globin synthesis
tissue is LEFT behind
shift to the LEFT
Hgb F
Met HB
👇 H+ 👆 pH
👇 temp
👇 altitude
👇 2 3 DPG/BPG
*when you shift the curve to the right, you 👇 the y axis (SaO2)
*O2 is less in the hgb
*O2 is being given to the tissue
*shift to the RIGHT
👆 H+👇 pH
👆 temp
👆 altitude
👆 H+2 3 DPG/BPG