haemostats Flashcards
what is the introduction to haemostats
fast localised process but complex, body works to prevent blood loss and create blood clot
what is the name of the first phase of haemostats
vascular spasm
describe the vascular spasm stage
blood vessel is torn, causing a reflex of vasoconstriction of blood vessels when damaged, platelets release granules which cause releases of serotonin/ADP prolonging vasoconstriction
what is the name of the second phases part 1
platelet adhesion
describe platelet adhesion
platelets stick to damaged blood vessels forming a plug to prevent blood loss
what is the name of phase 2 part 2
platelet release reaction
describe platelet release reaction
when platelets adhere to damaged blood vessels they become activated, change shape and develop projections causing other platelets adhere to they forming a bigger plug preventing blood loss releasing granuals causing release of ADP/seratonin
what is the name of phase 2 part 3
platelet aggregation
describe platelet aggregation
release of chemicals cause other platelets to migrate to the specific site the chemicals were released from
what is the name of phase 3
coagulation
describe coagulation
complex response in reaction where various chemicals known as clotting factors will activate each other
prothrombinase forms
prothrombinase coverts prothrombin into thrombin
thrombin converts fribrinigen into fibrin
what are the 4 signs and symptoms of inflammation
redness
swelling
heat
pain
what can the acute inflammatory be caused by
microbial infection
irritant and corrosive chemicals
tissue necrosis
physical agents
what are the osmotic changes of vasodilation
cell wall permeability/capillary blood flow increases
how long does vasoconstriction last
5-10mins
