Haematology Flashcards

1
Q

B12 metabolism

A

Released from proteins
Binds to intrinsic factor
Absorbed in terminal ileum

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2
Q

When to transfuse

A

If hb

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3
Q

Philadelphia chromosome

A

BCR-ABL gene fusion of chromosomes 9 and 22
CML

Sometimes ALL

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4
Q

What are Aeur rods characteristic of ?

A

AML

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5
Q

Howell jolly bodies

A

Hyposplenism

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6
Q

Pappemheimer bodies
Siderotic granules
Acanthocytes

A

Hyposplenism

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7
Q

Target cells

A

Hyposplenism

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8
Q

Pencil poikilocytes

A

Iron deficiency anemia

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9
Q

Target cells

A

Iron deficiency or hyposplenism

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10
Q

Tear drop poikilocytes

A

Myelofibrosis

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11
Q

Schistocytes

A

Intravascular haemolysis

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12
Q

Hyper segmented neutrophilia

A

Megaloblastic anaemia

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13
Q

Role of VWf

A

Promotes platelet adhesion to damaged endothelium

Carrier molecule for VIII

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