Gynecologic Oncology Flashcards

1
Q

Type of hydatidiform mole that is positive for p57Kip2 immunostaining

A

Partial mole

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2
Q

Paternal age is a risk factor for this type of hydatidiform mole

A

Complete mole

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3
Q

Beyond this age, the risk of acquiring a hydatidiform mole is increased ten-fold

A

40 years

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4
Q

Sonographic sign of complete hydatidiform mole on pelvic ultrasound in the second trimester

A

Snowstorm-like appearance

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5
Q

Drug of choice in chemoprophylaxis for malignant degeneration of hydatidiform moles

A

Methotrexate

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6
Q

Preferred contraceptive method after a molar pregnancy

A

Low dose oral contraceptive pills

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7
Q

A rare neoplastic proliferation of intermediate trophoblasts that invade the myometrium at the placental site after a pregnancy

A

Placental site trophoblastic tumor

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8
Q

A rare trophoblastic neoplasm which is the malignant counterpart of intermediate trophoblasts of the chorion leave

A

Epithelioid trophoblastic tumor

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9
Q

A tumor or tumor-like process invading the myometrium and characterized by trophoblastic hyperplasia and persistence of placental villous structures

A

Invasive mole

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10
Q

An epithelial malignancy of trophoblastic cells formed by the abnormal proliferation of cytotrophoblasts and syncytiotrophoblasts in the absence of chorionic villi

A

Choriocarcinoma

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11
Q

According to the 2000 FIGO Anatomic Staging, a gestational trophoblastic neoplasia with metastases only to the lungs are assigned as:

A

Stage III

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12
Q

Karyotypes of partial hydatidiform moles

A

69,XXX

69,XXY (more common)

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13
Q

[Multiparity / Nulliparity] triples relative risk of acquiring endometrial cancer.

A

Nulliparity

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14
Q

A histopathologic finding that is described as a single papilla lined by tumor cells and contains a central vessel. This is pathognomonic of yolk sac tumors.

A

Schiller-Duval body

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15
Q

A complete hydatidiform mole has a [lower / higher] chance of malignanr sequelae than partial moles

A

Higher (15%, compared to 4-6% for partial moles)

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16
Q

Management of cervical low grade squamous intraepithelial lesion

A

Colposcopy and biopsy

17
Q

Maternal exposure to diethylstilbestrol predisposes a female fetus to developing this cancer:

A

Vaginal clear cell adenocarcinoma