GORD Flashcards
What is the function of Intrinsic Factor produced in the stomach?
Allows absorption of Vitamin B12 in the terminal ileum
What is the function of the drug ‘Omeprazole’ on the GI tract?
Inhibition of Proton Pump to reduce acid secretion
Which type of histamine is found in the gastric parietal cells?
Histamine 2
What do D cells produce?
Somatostatin
Where does the Common Bile Duct drain into?
Duodenum
How do non steroidal anti inflammatory drugs (NSAIDs) irritate the stomach?
By inhibition of gastrointestinal mucosal cyclo-oxygenase (COX) activity
How many layers of muscle are present in the stomach wall?
3
What is the action of the proton pump in the parietal cells of the stomach?
K+ into cell, H+ out of cell
Which of the following vessels supplies arterial blood to the Jejunum?
Superior mesenteric artery
Porta hepatis
Left and right hepatic arteries
Portal vein
Hepatic branch of vagus nerve
Left and right hepatic ducts
What is the change in cell-type (‘metaplasia’) seen in the lower oesophagus after prolonged reflux of acid?
Stratified squamous to columnar
Vagus nerve
part of the parasympathetic system and releases acetylcholine onto parietal cells
What is secreted by enterochromaffin cells?
Histamine
What is the first location that Fat is acted upon by Lipase enzymes when passing through the GI tract?
Oral cavity
What is secreted by G cells?
Gastrin