GORD Flashcards

1
Q

What is the function of Intrinsic Factor produced in the stomach?

A

Allows absorption of Vitamin B12 in the terminal ileum

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2
Q

What is the function of the drug ‘Omeprazole’ on the GI tract?

A

Inhibition of Proton Pump to reduce acid secretion

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3
Q

Which type of histamine is found in the gastric parietal cells?

A

Histamine 2

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4
Q

What do D cells produce?

A

Somatostatin

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5
Q

Where does the Common Bile Duct drain into?

A

Duodenum

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6
Q

How do non steroidal anti inflammatory drugs (NSAIDs) irritate the stomach?

A

By inhibition of gastrointestinal mucosal cyclo-oxygenase (COX) activity

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7
Q

How many layers of muscle are present in the stomach wall?

A

3

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8
Q

What is the action of the proton pump in the parietal cells of the stomach?

A

K+ into cell, H+ out of cell

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9
Q

Which of the following vessels supplies arterial blood to the Jejunum?

A

Superior mesenteric artery

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10
Q

Porta hepatis

A

Left and right hepatic arteries
Portal vein
Hepatic branch of vagus nerve
Left and right hepatic ducts

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11
Q

What is the change in cell-type (‘metaplasia’) seen in the lower oesophagus after prolonged reflux of acid?

A

Stratified squamous to columnar

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12
Q

Vagus nerve

A

part of the parasympathetic system and releases acetylcholine onto parietal cells

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13
Q

What is secreted by enterochromaffin cells?

A

Histamine

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14
Q

What is the first location that Fat is acted upon by Lipase enzymes when passing through the GI tract?

A

Oral cavity

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15
Q

What is secreted by G cells?

A

Gastrin

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16
Q

What is secreted by chief cells?

A

Pepsinogen