Gluconeogenesis Regulation (Week 5) Flashcards
1
Q
Where does gluconeogenesis occur?
A
Liver and kidneys
2
Q
Outline how gluconeogenesis works
A
Uses pyruvate as lactate and converts it to glucose.
3
Q
Name the five substrates of gluconeogenesis.
A
Pyruvate Lactate Amino acids Glycerol TCA cycle intermediates
4
Q
Where is the Glucose-6-phosphate enzyme found?
A
The endoplasmic reticulum of the liver cells
5
Q
What is the basic premise of reciprocal regulation?
A
When energy is needed or blood glucose is high glycolysis will predominate.
When there is a surplus of energy and blood glucose is low, gluconeogenesis will take over.
6
Q
How is pyruvate carboxylate activated in the liver.
A
High energy levels
7
Q
In the liver, when is glycolysis stimulated?
A
High blood sugar
Low energy
8
Q
In the liver, when is gluconeogenesis stimulated?
A
Low blood sugar
High energy
