Glaucoma and Vertigo Drugs Flashcards
The following drug classes decrease auqueous humor synthesis:
- Beta-blockers
- Alpha-2 agonists
- Carbonic anhydrase inhibitors
During pregnancy ___ can be used ONLY if absolutely necessary
Promethazine (anti-emetic/1st generation antihistamine)
Vertigo: Medications to suppress the vestibular system and ease nausea
Benzodiazepine anxiolytics
- Diazepam
- Lorazepam
Vertigo: Medications to suppress the vestibular system and ease nausea
Antiemetics
- Ondansetron
- Prochlorperazine
- Promethazine (1st generation antihistamine)
Meniere disease: Medications to suppress vestibular system and ease nausea.
THE SAME AS FOR VERTIGO EXCEPT
No 2nd generation antihistamines (loratadine, fexofenadine, cetirizine)
Meniere disease: Treatment to modulate endolymph/ionic balance
Initial treatment
Restrict dietary salt intake
Vertigo: Medications to suppress the vestibular system and ease nausea
2nd generation antihistamines
- Loratadine
- Fexofenadine
- Cetirizine
Meniere disease: Treatment to modulate endolymph/ionic balance
2nd step in treatment
Hydrochlorothiazide (thiazide diuretic)
Alone or with:
Triamterene (K-sparing diuretic) and/or acetazolamide (CA inhibitor)
3rd line treatment for chronic open-angle glaucoma
- Dorzolamide (CA inhibitor) +
- Pilocarpine (direct muscarinic antagonist)
2nd line treatment for chronic open-angle glaucoma
- Timolol (beta-blocker) or
- Apraclonodine (alpha-2 agonist)
___ during pregnancy are typically only for cases of heart disease (not for normal HTN); not typically used to treat Meniere disease
Diuretics
___ are pregnancy risk factor D and should not be used unless benefits outweight the risks.
Benzodiazepines
Diazepam
Lorazepam
The following drug classes enhance drainage of aqueous humor
- Muscarinic agonists
- Prostaglandins
Vertigo: Medications to suppress the vestibular system and ease nausea
1st generation antihistamines
- Dimenhydrinate
- Diphenhydramine
During pregnancy ___ and ___ can be used for vertigo/nausea
Dimenhydrinate
Diphenhydramine
(1st generation antihistamines)