GI Infections -22.01.24

Question 1

How does the normal micro biome of the GI tract discourage infection (2 ways)

Answer 1

• Inhibiting overgrowth of endogenous pathogens
• Preventing colonisation by exogenous pathogens

Question 2

What can disrupt the balance of the normal flora in the GI tracts

Answer 2

• Antibiotics
• Peritonitis (physical protrusion of gi tract into abdominal cavity)

Question 3

What prevents infection in GI tract?

Answer 3

Gastric acid

Question 4

Causes of diarrhoea

Answer 4

Infective e.g. cholera
Inflammatory e.g. Crohn’s
Loss of absorptive area e.g. coeliac
Pancreatic disease e.g. pancreatitis, cancer
Drugs e.g. antibiotics
Colon cancer e.g. thyroitoxicosis
Systemic disease

Question 5

Mechanisms of watery and bloody,mucoid stool

Answer 5

Watery -

Non-inflammatory

Bloody,mucoid -

Inflammatory

Question 6

Location of watery and bloody,mucoid stool

Answer 6

Watery -

Proximal small bowel

Bloody,mucoid -

Colon