Geriatrics pt.2 Flashcards
What is polypharmacy?
The excessive or inappropriate use of medications
Adults over 65 purchase over __% of all prescription meds
30%
Older adults are more likely to experience adverse drug reactions (ADRs) and ___ of older people take at least 1 unnecessary drug
1/2
Avg. older adult takes 5 meds
Avg. nursing home resident takes 7 meds
What are the causes of polypharmacy?
● Physicians may prescribe medications to relieve symptoms that could be relieved through nonpharmacologic methods
- Ex- a patient who naps during the day cannot sleep at night and is prescribed a sleeping pill
● Patients may obtain prescriptions from multiple providers
● Patients may take over the counter medications that interact with
other medications
- Interactions may be seen as new symptoms, resulting in new medications prescribed
What are characteristics of polypharmacy in older adults?
● Use of medications for no apparent reason
● Use of duplicate medications
● Concurrent use of interacting medications
● Use of contraindicated medications
● Use of inappropriate dosage
● Use of drug therapy to treat adverse drug reactions
How does aging affect drug absorption?
● Decreased gastric acid
● Decreased stomach emptying
● Decreased gastric motility
How does aging affect drug distribution?
● Decreased body H2O
● Increased body fat
● Decreased plasma proteins
● Decreased lean body mass
How does aging affect drug metabolism?
● Decreased liver mass
● Decreased blood flow to liver
● Decreased enzyme activit
How does aging affect drug secretion?
● Decreased kidney mass
● Decreased blood flow to kidneys
● Decreased nephron function
What medications are most commonly overprescribed?
● Laxatives
● BP meds
● Diuretics
● DM meds
Likely due to side effects of other meds and because quick fix
What drug commonly causes gastrointestinal side effects?
NSAIDs
What drug has a common side effect of sedation?
Opioids
What drugs commonly cause confusion as a side effect
Antidepressants
Analgesics
Lithium
What drugs commonly cause depression as a side effect?
Barbiturates
Antihypertensives
What drug typically causes orthostatic hypotension as a common side effect?
Antihypertensives
What drugs cause fatigue/weakness as a common side effect?
Diuretics
Glucocorticoids
What can we, as PTs, do to help prevent polypharmacy?
Carefully review patient’s medication list
● Look for any possible adverse drug reactions
● Does their medication list make sense with their comorbidities? (Ex. taking antibiotics from an infection years ago?)
● Think about how medications will affect physical therapy (Dosing schedules, RPE)
● PATIENT EDUCATION
___ % of people over ages 65 reported at least one fall in a year
29%
Wha is the leading cause of death/hospitalization from injury in older adults?
Falls
- Medical treatment costs >$50 billion/yr
- Can occur with or without injury
- Associated with pain, loss of confidence, functional decline, and institutionalization
What are some environmental risk factors for falls?
● Slippery or uneven surfaces
● Rugs
● Poor lighting
● Obstacles in path (Cords, clutter)
● Lack of grab bars or handrails
● Poorly arranged furniture
What are some risk factors for falling?
- CVA/neuro diagnosis
- prior falls/ fear of falling
- recent hospitalization
- poor sensation/ pain/ LE weakness/ frailty
- difficulty with ADLs
- age 65+
- use of assistive device
- orthostatic hypotension
- polypharmacy
- incontinence
- depression or anxiety
- foot problems
- cog impairment
- meds like benzodiazepines, diuretics, sedatives
What is the 6th vital sign*?
Gait speed but not really
good for indication of fall risk
Gait speed is correlated with what outcomes?
● Re-hospitalization
● ADL performance
● Number of medications
● Depressive symptoms
● Discharge location from hospital
● History of multiple falls
What is the cut-off for community ambulation?
0.8 m/s