Genetics Flashcards
1
Q
Name 3 sensor proteins and what they do
A
AMPK - senses changes in energy status in the cell
Calmodulin - senses calcium in the cell and informs muscle cells of a contraction and stimulates expression of slow twitch muscle fibre genes
Mechanoreceptors - detect pressure on the skin. Links muscle loading to protein synthesis
2
Q
Name 2 signalling proteins and what they do
A
Kinases - phosphorylate a target protein inducing a conformational change
Phosphatases - dephosphorylate a target protein inducing a conformational change
3
Q
What mechanisms are there to modulate the genome of adults for sporting advantage?
A
Somatic gene transfer of IGF-1,
Selective breeding,
Gene knockout - down regulation of Myostatin (negative regulator of muscle growth)
