Genetic Screening Flashcards
1
Q
1st trimester screening
A
10-13 weeks
Nuchal translucency, hcg, Papp A
2
Q
2nd trimester Quad screen
A
15-22 weeks
Hcg, AFP, estriol, inhibin A
3
Q
Integrated screen
A
1st trimester US and Papp A + 2nd trimester quad
Hold results
4
Q
Sequential screen
A
1st trimester + quad, don’t hold results
5
Q
Abnormal AFP or isolated low Papp A
A
Increased SAB, IUFD, SIDS, FGR, PTD, gHTN
6
Q
Absolute contraindications to Methotrexate
A
IUP
Immunodeficiency
Anemia, leukopenia, thrombocytopenia
Sensitivity
Pulmonary dz, peptic ulcer dz
Hepatic/Renal dysfunction
Breastfeeding
Ruptured, unstable, poor f/u
7
Q
Relative contraindications to methotrexate
A
Cardiac activity
High initial hcg
>4cm
Refusal of blood products
