Genetic factors - PK Flashcards
1
Q
What is Single nucleotide polymorphisms
A
A single nucleotide that differs between patients
2
Q
What is Synonymous SNP?
A
Both alleles of gene encode the same polypeptide
3
Q
What is Non synonymous SNP?
A
The allele encode a different polypeptide
4
Q
What is pharmacogenetics?
A
The study of how individual patients’ genome affects their response to a drug
5
Q
What is Monogenic?
A
A single gene affects the response
6
Q
What is Polygenic?
A
Multiple genes affect the response
