Ganong 24th ed - Chapter 7 - Neurotransmitters (1)

Question 1

In general, which tissues contain muscarinic cholinergic receptors?

Answer 1

Smooth muscle, glands, brain.

Question 2

In general, which tissues contain nicotinic cholinergic receptors?

Answer 2

Skeletal muscle, sympathetic ganglia, brain.

Question 3

Nicotinic receptors: are they ionotropic or metabotropic?

Answer 3

Ionotropic.

Question 4

Nicotinic receptors: how many subunits? What is the effect of ACh binding?

Answer 4

5 subunits. ACh binding causes the pore to open, and then sodium moves into the cell and potassium moves out.

Question 5

Muscarinic receptors: are they inotoropic or metabotropic?

Answer 5

Metabotropic.

Question 6

Muscarinic receptors: What class of receptor are they?

Answer 6

G-protein coupled