Formulas Flashcards
Covert C to F
F= (C * 1.8) +32
Convert F to C
C = (F-32)/1.8
% w/v
X g/ 100 mL
% v/v
X mL/ 100 mL
%w/w
X g/ 100 g
Precent Strength =
100/ ratio strength
Ratio Strength =
100/ percent strength
PPM –> Percentage Strength
move the decimal LEFT 4 places
Percentage Strength –> PPM
move the decimal RIGHT 4 places
Specific Gravity =
G / mL
mOsmol/L =
wt of substance (g/L) / MW (g/mole) * # of particles * 1,000
Isotonicity (E) =
(58.8) (i) / (MW of drug)(1.8)
moles =
Gram/ MW
mmoles =
mg / MW
mEq =
mg * valence / MW
OR
mmols * valence
Enteral Nutrition
Carbs:
Protein:
Fat:
Carbs: 4 kcal/g
Protein: 4 kcal/g
Fat: 9 kcal/gram
Parenteral Nutrition
Dextrose:
Amino Acid:
ILE 10%:
ILE 20%:
ILE 30%:
Dextrose: 3.4 kcal/g
Amino Acid: 4 kcal/g
ILE 10%: 1.1 kcal/ml
ILE 20%: 2 kcal/ml
ILE 30%: 3 kcal/ml
Determine Fluid needs
when weight > 20 kg:
1500 mL + (20mL)(wt in kg - 20)
Total Energy Expenditure
TEE = BEE * activity factor * stress factor
grams of nitrogen from protein
N = protein intake (g) / 6.25
Corrected calcium (from when albumin < 3.5)
Ca reported + [(4-albumin) * .8]
BMI
[weight (lbs) / (ht in inches)^2 ] * 703
IBW males:
IBW females:
IBW males: 50 + (2.3 * inches. over 5 ft)
IBW females: 45.5 + (2.3 * inches over 5 ft)
Adjusted Body weight
IBW + .4 (TBW-IBW)
–> use for aminoglycosides (obese)
What drugs do you use IBW always
-acyclovir
-aminophylline
-levothyroxine
-theophylline
Flow rate/Drop factor (drops/min)
drop / mL * mL/hr * hr/60 min
How to determine dehydration based on lab values
BUN:Scr = 20:1
Anion gap
Na- Cl - HCO3
pH calculation for weak acid
pH = Pka + log (salt/acid)
pH calculation for weak base
pH = Pka + log (base/salt)
% ionization for weak acid
100 / ( 1+ 10 ^(Pka- pH)
Time to burn
TTB = SPF * TTB (w/o sunscreen)
% ionization for weak base
100 / ( 1+ 10 ^ (pH - PKa)
Absolute Neutrophil Count
ANC = WBX * [ (segs + bands) / 100]
Pack year smoking history
cig packs/day * years smoked
Friedewald Equation
LDL = TC - HDL - (TG/5)
*do not use if TG > 400
Minimal weighable quantity (MWQ)
(sensitivity requirement) / (acceptable error rate - usually 0.05)
BSA calculation
sq rt [ (ht in cm * wt in kg) / 3600]
Bioavailability (F)
100 * (AUC extravas / AUC intravas) * (dose inta/ dose extra)
Volume of distribution
(amount of drug in the body) / (concentration of drug in the plasma)
Clearance (cl)
F * dose / AUC
OR
ke * Vd
Elimination rate constant (ke)
Cl/ Vd
Predicting Drug Concentrations
C2 = C1 * e ^(-kt)
ke = (ln (c1/c2)) / t
Half life (t 1/2)
0.693 / ke
Loading Dose
(desired concentration * vd) / F
Mean arterial Pressure (MAP)
[ (2 * diastolic pressure) + systolic pressure] / 3
Phenytoin (total) correction for albumin < 3.5
(total. phenytoin measured) / (0.2 * albumin) + 0.1