Fluoroquinolonas/quinolonas Flashcards

1
Q

Que son las quinolonas?

A

AB bactericidas de amplio espectro, potentes en la eliminacion de gram - aerobias

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2
Q

Contraindicaciones quinolonas

A
  • menores 18 años

- embarazadas

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3
Q

Como es la distribucion de las quinolonas

A

Por todos los tejidos incluyendo snc

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4
Q

Mecanismo de accion quinolonas

A
  • inhiben la polimerass del ADN intracel bacteriano (enzima para la duplicacion y transcripcion del adn bact)
  • consume O2 (no elimina bacterias anaerobias)
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5
Q

Para que se usan la presentación oral y la parenteral? (Quinolonas)

A

Oral: inf moderadas
Parenteral: intensas

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6
Q

Uso terapéutico quinolonas.

A

Infecciones:

  • snc
  • hueso
  • articulaciones
  • musc
  • vias resp alta y baja
  • sist dig
  • its
  • vias urinarias jlablabla
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7
Q

Que farmacos estan aqui? (Quinolonas)

A
  • Ciprofloxacina
  • levofloxacina
  • norfloxacina
  • lomelofloxacina
  • moxifllxacina
  • ofloxacina
  • acido naldixico
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8
Q

Vm quinolonas

A

12 hr

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9
Q

Quinolona que se resevar pra usarse en uci en vias resp bajas e inf extensas

A

Moxifloxacina

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10
Q

Primera quinolona ussdo para tx cistitis

A

Acido naldixico

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11
Q

Adv quinolonas

A
  • estimulación central
  • hepatonefrotoxicod
  • colitis pseudomembranosa
  • epigastralgia
  • pueden romper el tendon de aquiles
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12
Q

Recomendaciones/precauciones

A
  • tener presente el peso corporal, sexo y edad
  • no adm a enf mentales, hepaticos, renales y reumaticos.
  • antiacidos gastricos, productos lacteos y calcio disminuyen su absorcion duodenal.
  • puede participar del coctel antibiotico
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