Final Exam Last Minute Info Flashcards
1
Q
- protease inhibitor
- increases cholesterol and triglycerides
- strong inhibitor of CYP3A4
A
Darunavir
2
Q
- protease inhibitor
- prolongs PR interval of ECG
- hyperbilirubinemia (yellow in whites of eyes)
A
Atazanavir
3
Q
- protease inhibitor
- prodrug
- skin reactions including Stevens Johnson Syndrome
A
Fosamprenavir
4
Q
- protease inhibitor
- nephrolithiasis warning (kidney stones)
- administer on empty stomach
A
Indinavir
5
Q
- protease inhibitor
- allergic reaction warning (more important b/c listed as a warning)
A
Ritonavir
6
Q
- protease inhibitor
- prolongs QT interval - pt should get EKG before therapy
A
Saquinavir
7
Q
- protease inhibitor
- intracranial hemorrhage in combination with Ritonavir
- take with a high fat meal
A
Tipranavir
8
Q
protease inhibitor combo consisting of Ritonavir and Lopinavir
A
Kaletra
9
Q
- fusion inhibitor for Tx of HIV-1
- not approved for children under age of 6
- rotate injection site
A
Enfuvirtide
10
Q
- entry inhibitor for Tx of HIV-1 (prevents entry of virus into host cell)
- St John’s Wort significantly decreases drug levels (so you’d need to give a higher dose)
A
Maraviroc
11
Q
- integrase inhibitor for Tx of HIV-1
- increased creatine kinase (causes myopathy)
A
Raltegravir
12
Q
Luminal amebicides
A
- Iodoquinol
2. Paramomycin
13
Q
Tx of amebic colitis
A
- metronidazole
2. luminal amebicides
14
Q
-DOC for eradication of the dormant liver forms due to P. vivax (malaria)
A
Primaquine
15
Q
- main indication for this drug is for Tx of chloroquine-resistant falciparum malaria
- not for prophylaxis
A
Quinine
