Fermentation Flashcards
Define fermentation
Occurs in the cytoplasm, glucose is only partially oxidized, 2 ATP per glucose, produced by substrate level phosphorylation. All have NAD+ regenerated
Lactic acid fermentation
- Pyruvate is the electron acceptor, lactate is the product
- Microorganisms, higher plants, and vertebrate muscle tissue
- Lactate dehydrogenase
Alcoholic fermentation
- Yeasts and some plant cells
- Requires 2 enzymes to metabolize pyruvate to ethanol
- Products are ethanol, CO2, and 2 ATP
- Used to produce alcoholic beverages, ethanol fuel, and non-sourdough bread
Why is fermentation necessary under anaerobic conditions?
Fermentation is necessary under anaerobic conditions because it allows the cell to regenerate NAD+ from NADH to keep glycolysis going. Under aerobic conditions, NAD+ is regenerated when NADH is oxidized at the electron transport chain of the mitochondria.
Catabolic and anabolic pathways
catabolic - polysaccharides are hydrolyzed to glucose, which enter glycolysis. Lipids are broken down into to glycerol. anabolic - glycogenesis - citric acid cycle and glycolysis are reduced to glucose.