fatty tumors Flashcards

1
Q

age intraosseous lipoma

A

30-60yo

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2
Q

location intraosseous lipoma

A

fibular, femur, tibia, calcaneus

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3
Q

bone location intraosseous lipoma

A

M

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4
Q

soft tissue lipoma age

A

30-50yo

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5
Q

soft tissue lipoma location

A

subcutaneous tissues of back, extremities, thorax

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6
Q

pathophysiology intraosseous lipoma stages

A
1 = viable non necrotic fat w/ trabecular resorption
2 = viable fat, fat necrosis and dystrophic ca++
3 = involution of the lesion
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7
Q

rad app intraosseous lipoma

A

lucent lesion w/ thin sclerotic border

  • can have lobulations/septations
  • dystrophic central ca++
  • can expand
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8
Q

rad app of intraosseous lipoma in different stages

A
1 = lucent
2 = lucent, sometimes expansile, lesion w/ central ca++
3 = lucent lesion w/ sclerotic border; w/ or w/o central ca++
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9
Q

intraosseous lipoma in calcaneus sign

A

Cockade sign

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10
Q

intraosseous lipoma MRI

A

high T1 low T2

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11
Q

hibernoma definition

A

rare benign fatty tumor from brown fat

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12
Q

age hibernoma

A

20-40yo

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13
Q

clinical symptoms hibernoma

A

slow growing painless mass

-symptoms d/t compression of adjacent structures

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14
Q

cytogenic analysis hibernoma

A

11q13 translocation

helps ddx from liposarc

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15
Q

location hibernoma

A

where normal brown tissue is present = thigh, shoulder, back, neck, chest, arm
(rare in retroperitoneum)

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16
Q

CT hibernoma

A

attenuation b/t fat and muscle ; enhances slightly w/ contrast and may have prominent feeding vessel

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17
Q

MRI hibernoma

A

high T1 and T2; but slightly less than subcu fat

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18
Q

DDX hibernoma

A

liposarc, rhabdomyoma, resolving hematoma

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19
Q

tx hibernoma

A

surgical excision

no hx of recurrence or malignant transformation/mets

20
Q

juxta-articular adiposis dolorosa subtype of…

A

Dercum disease

21
Q

dercum disease characterized by…

A

multiple painful lipomas

22
Q

M or F? dercum disease

A

F

45-60 yo and overweight/menopausal

23
Q

MC location dercum disease

A

legs and trunk
*medial knee
can be anywhere

24
Q

dercum disease radiographically indistinguishable from…

A

lipoma

25
Q

2nd MC malignant ST tumor

A

liposarcoma

26
Q

liposarcoma is ___% of all malignant ST tumors

A

20

27
Q

soft tissue liposarc age

A

middle-elderly patients

rare in children

28
Q

most lipomatous tumors in infants/children are…

A

lipoblastomas

29
Q

ST liposarcs location

A

thigh, glutes, retroperitoneum, and leg

30
Q

bony liposarc location

A

tibia, femur

any region of bone w/ extension

31
Q

rad appearance liposarc

A

nonspecific

osteolysis - can be poorly or well defined

32
Q

CT liposarc

A

areas of low attenuation

may not include areas of fat

33
Q

MR liposarc

A

variable; 50-80% show fat density

will enhance w/ gad

34
Q

tx leiomyoma

A

surgical excision

35
Q

CT leiomyoma

A

calcified solitary or multiple ST masses

mimic cartilaginous matrix

36
Q

DDX leiomyoma

A
calcifying schwannoma
(near NV bundle)
extraskeletal OS
synovial sarc
ST chondroma
tumoral calcinosis
MO
37
Q

3rd MC ST sarcoma

A

leimyosarcoma

38
Q

leimyosarcoma % that arise in peripheral extremity ST

A

12-41

39
Q

most commonly leimyosarcoma arise in..

A

thigh

40
Q

1/3 of ST leimyosarcoma arise from….

A

small vein

41
Q

rad app leimyosarcoma

A

poorly defined lytic lesion; w/ or w/o ST mass

42
Q

bone location leimyosarcoma

A

M

43
Q

location leimyosarcoma

A

femur/tibia

**around knee

44
Q

highest overall mortality for sarcomas

A

leiomyosarcoma

45
Q

mets w/ leimyosarcoma

A

lung

-then liver, bone, ST, LN

46
Q

prognosis worse w/ this location of leimyosarcoma

A

retroperitoneal