(F) L2 Malignant WBC disorder Flashcards
a disease of leukocytes in the blood and bone marrow; uncontrolled proliferation of a clone of malignant WBCs
Leukemia
solid tumor neoplasms of lymphoid tissues
lymphoma
2 main types of lymphoma
- Hodgkin
- Non-hodgkin
form of cancer of the plasma cells
myeloma
non malignant tumors are caused by
congenital genetic abnormalities
General characteristics of hematologic neoplasm
(acquired / congenital) genetic disease
acquired
patient acquires the disease sometime in life due to consistent genetic
Non-malignant yung congenital
General characteristics of hematologic neoplasm
type of infection as well as the treatment
Systemic infection, therefore treatment MUST also be systemic
ex; chemotherapy, radiation, supportive therapy, targeted therapies, hem
General characteristics of hematologic neoplasm
of unkown cause
idiopathic
except environmental factors like radiation and chemical exposure
Agents / Factors affecting occurence of leukemias and lymphomas
Matching type
a. Genetic and immunological factors
b. Genetic abnormalities and association
c. Viral agents
____1. Down syndrome, Fanconi anemia
____2. Translocation B and A interchange
____3. Age
____4. Mutations in a single gene
____5. Epstein B
ABAAC
Agents / Factors affecting occurence of leukemias and lymphomas
types of exposure that can become factors in the occurence of leukemias and lymphomas (3)
environmental, chemical, and drug exposure