Eye Pathology Flashcards

1
Q

Persistant irdopupillary membrane is caused by?

A

remnants of a fetal membrane that persist as strands of tissue crossing the pupil.
source of blood supply for the lens in fetus
normally atrophies from the time of birth to the age of four to eight weeks. If fails  PIPM

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2
Q

in PIPM failure for atrophy of membrane in cornea results in?

A

Corneal opacities

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3
Q

in PIPM failure for atrophy of membrane lens results in?

A

cataracts

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4
Q

both pinguecula and ptyregium can manifest to

A

SCC or melanoma

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5
Q

Conjuctival melanomas appear

A

Pigmented or non pigmented raised lesion that appears in ADULT life

Has a strafed epithelium, malignant melanocytic cells, exist in the basal layer of the conjunctiva.

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6
Q

Conjuctival melanomas appear

A

on one side,
light skinned people,
middle age

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7
Q

Choroid melanoma’s are the

A

Most common primary intra-ocular malignancy in White adults in North America and Europe

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8
Q

Retinablastoma is in which chromosome?

A

Ch 13 band 14

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9
Q

Retinoblastoma gross appearance?

A

white exophytic growth from the retina in to the vitrious fluid

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10
Q

Retina blastoma micro appearance?

A

neoplastic cells have a large basophilic nucleus with little cytoplasm

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11
Q

Flexner Winter-steiner rosettes

are

A

Clusters of cuboidal or columnar cells arranged around a central lumen.
Nuclei aredisplaced away from lumen.

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12
Q

Homer Wright rosettes

are

A

Radial arrangements of cells around a central tangle of fibrils.

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13
Q

Flexner Winter-steiner rosettes and Homer Wright rosettes

are seen in?

A

Retinoblastoma

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