Eye Pathology Flashcards
Persistant irdopupillary membrane is caused by?
remnants of a fetal membrane that persist as strands of tissue crossing the pupil.
source of blood supply for the lens in fetus
normally atrophies from the time of birth to the age of four to eight weeks. If fails PIPM
in PIPM failure for atrophy of membrane in cornea results in?
Corneal opacities
in PIPM failure for atrophy of membrane lens results in?
cataracts
both pinguecula and ptyregium can manifest to
SCC or melanoma
Conjuctival melanomas appear
Pigmented or non pigmented raised lesion that appears in ADULT life
Has a strafed epithelium, malignant melanocytic cells, exist in the basal layer of the conjunctiva.
Conjuctival melanomas appear
on one side,
light skinned people,
middle age
Choroid melanoma’s are the
Most common primary intra-ocular malignancy in White adults in North America and Europe
Retinablastoma is in which chromosome?
Ch 13 band 14
Retinoblastoma gross appearance?
white exophytic growth from the retina in to the vitrious fluid
Retina blastoma micro appearance?
neoplastic cells have a large basophilic nucleus with little cytoplasm
Flexner Winter-steiner rosettes
are
Clusters of cuboidal or columnar cells arranged around a central lumen.
Nuclei aredisplaced away from lumen.
Homer Wright rosettes
are
Radial arrangements of cells around a central tangle of fibrils.
Flexner Winter-steiner rosettes and Homer Wright rosettes
are seen in?
Retinoblastoma