Extra Derm Flashcards
pityriasis (tinea) versicolor - describe lesions
- who
- where
pale, velvety hypopigmented macule which is non scaly. There may be scaling on scraping of the lesions
seen in Britain after sun tanning abroad, causes depigmentation of tanned skin and increased pigmentation of untanned skin
commonly occurs on chest, back and shoulders
treatment of pityriasis (tinea) versicolor
antifungal agents
eg ketoconazole cream
or oral terbinafine
what is erythema nodosum associated with
sarcoidosis, TB , IBD
OCP, penicillin, sulphonamide
describe erythema nodosum
erythematous raised nodules on anterior shins
what is dermatitis herpetiformis associated with
coeliac disease - look for symptoms of GI disturbance and malabsorption in history
DH and coeliac are due to intolerance of gliadin fraction of gluten - triggers production of IgA antibodies and an autoimmune process that targets the skin and gut
describe dermatitis herpetiformis lesions
symmetrical and typically affect the extensor surfaces of elbows, knees upper back and buttocks
intensely itchy
which Ab are present in dermatitis herpetiformis
anti-endomysial
what does skin biopsy show in dermatitis herpetiformis
IgA deposits along dermal papillae
treatment of dermatitis herpetiformis
gluten free diet and Dapsone
asteatotic eczema
common in elderly people, thought to be due to over washing and dry winter climate
commonly affects lower limbs causing dry itchy skin adn characteristic ‘crazy paving’ pattern
what is asteatotoic eczema treated with
emollients and steroids
what drugs and diseases are associated with asteatotic eczema
diuretic use
hypothyroidism
acanthosis nigricans
velvety skin in flexural areas of axillae and neck
associated with insulin resistance, obesity and PCOS
dermatological manifestations of HIV/AIDS
oral hairy leukoplakia
Kaposi’s sarcoma
Candidiasis
ichthyiosis
can be hereditary or acquired
causes dry fish-like scaling of the skin, particularly affecting the limbs
what are some causes of acquired ichthyosis
Hodgkin’s, sarcoidosis and internal malignancy
what is a genetic cause of ichthyosis
mutation in the filaggrin gene leads to impaired skin barrier and water loss from stratum corneum
- skin doesnt shed its dead skin cells
lupus erythematous
persistent, scaly disc like plaques on scalp, face and ears that may cause pigmentary changes, scarring and hair loss
chronic discoid:
