experience dependent development Flashcards
how is the LGN set up
retinotopically with both the left and right eye segregated
what is the hypercolumn
primary unit of analysis in the visual cortex. it contains eye specific information, color, orientation and intensity
How do ocular dominance columns develop”
overtime with experience
what is the basis of ocular dominance columns?
reorganization of inputs.
single RGC show progressive regression.
what does synchronous firing lead to?
leads to stabilization of synapses. fire together-wire together. out of sync-lose the link
what does layer V do?
integrates the signals from layer IV input.
what happens to ocular dominance columns after deprivation?
the columns are not equally distributed and the eye that is deprived will have much less input.
does visual experience also train cortical neurons?
yes.
what are critical periods
windows in time when visual performance can be shifted. they are different for each task, such as direction, binocularity, and stereopsis
are the mechansims for ocular dominance formation genetically determined?
NO.
what is involved in ocular dominance formation
their formation is sequential and involves competition
what are mechanisms of CP
glutamate receptor (NMDA) activation and calcium influx.
what is argument for NMDA receptors being responsible for CP
1) NMDA appears at time of CP onset.
2) dark-earing delays loss of receptors
evidence that GABA is important
1) GAD65 KO has delayed CP
2) enhancing function shifts CP earlier
3) benzos enhance CP
