Exam One Flashcards
Clostridium perfringens diagnosis
Gram pos rods, obligate anaerobe, beta hemolytic, detect toxins in food
Neisseria gonorrhoae diag
Gram neg diplococci, gram stain of urethral discharge on Thayer-Martin media in men, PCR and nucleic acid amplification in men and women, grows on chocolate agar
ASO test
Detects strep O confirming a recent GAS infection
Rickettsi r. diagnosis
Gram neg, obligate intracellular
Entamoeba histolytica diagnosis
Trophozoites in stool
T. gondi treatment
Sulfa drugs for CNA infections
Shigella diagnosis
Gram neg rods, oxidase neg, non motile, non lactose fermenter, stool culture
EIEC disease
Mucoid diarrhea (1-3 days)
GAS disease
Pharyngitis, scarlet fever, impetigo, necrotizing faciitis, TSS, sequelae of rheumatic fever, (glomerulonephritis, RBC’s and protein in urine)
H. flu treatment
Ampicillin, cephalosporins, type b vaccine
Mycoplasma pneumoniae treatment
Azithromycin (any macrolide), doxycycline
Entamoeba histolytica treatment
Metronidazole
Vibrio diagnosis
Gram neg rods, LPS antigen serotypes, cholera toxin in cholerae, seafood in others
Strep pneumonia diagnosis
Catalse negative, alpha hemolytic, optochin sensitive
Pseudomonas aeruginosa pathology
ExoA toxin, biofilms, CF patients, burn victims
Enterococcus f. pathology
biofilms
Bactrim
Folic acid synthesis and utilization inhibitor
Yersinia pestis disease
buboes, fever, chills
Rickettsia r. disease
spotted rash from per. to trunk
Taeniae solium
Tapeworm, undercooked pork, cysts and inflammation in brain, eyes, muscle, weight loss, praziquantel
GAS treatment
Penicillin V
Cryptosporidium disease and treatement
mild diarrhea, no treatment
Use for extended spec pennicilins
Increased gram neg, UTI’s otitis media, comm. pneumonia, H. Flu, Listeria, Lyme disease
T. gondi strucutre
Coccidian (non motile), intracellular, rising antibody titers
Chloramphenicol use and side effect
Aplastic anemia (protein synth inhibitor), RMSF if you can’t use tetracycline
Treponema pallidum is:
Syphillis
Extended spec pennicilins
Ampicillin, Amoxicillin, Pipericillin
Suflonamides and use
Folic acid inhibitors, no anaerobes, good for otitis media, sinusitis, bronchitis, shigella, salmonella, e. coli
Staph epidermis disease
Catheter/joint infections, endocarditis
Mycobacterium tuberculosis pathology
granulomatous inflammation and giant cells, infects macrophages and prevents fusion of vesicles to lysosomes
T. gondi disease
Fevers, mimics mono, encephalitis in aids patients
Schistosoma mansoni (everything)
Fluke, snails and mollusks, intravascular parasite, swimmers itch, hepatosplenomegaly, praziquantel, portal vein blockage due to egg reaction
Legionella pneumophilia diseases
Legionnaires, Pontiac lever (self limited flu like illness)
NonTB mycobacteria disease
Pulmonary disease, weight loss (avium), cutaneous infections (marinum)
EAEC pathology
Biofilm and enterotoxins
H pylori treatement
multiple antibiotics and proton pump inhibitor
Enterococcus f. diagnosis
Gram pos cocci in long chains, alpha hemolytic, bile-esculin positive
G. lamblia treatment
metronidazole
Borellia burgdorferi is:
Lyme
Giardia lamblia pathology
Beavers, attaches to intestine
Penicillin drug of choice?
Strep, Syphillis, Pneumococci
C. trachomatis disease
same as gonnorhea, wihout pharyngitis or DGI, but plus neonatal syndrome
Y. pestis treatment
streptomycin (aminoglycoside)
C. trachomatis pathology
EB enters cells, RB replicates, no immunity
Bordetella pertussis treatement
Erythromycin, any macrolide, DTaP vaccine, prophylaxis for contacts
Vancomycin
D-ala-D-ala interference, no gram neg coverage, red man syndrome
E coli strucutre
Gram neg rods, oxidase neg, lactose fermenter on MacConkey agar
Doxycyclin
Use against odd ones, such as Lyme
Legionella pneumophilia treatment
Azithromycin (any macrolide) or levofloxacin (any fluoroquinolone)
1st gen cephalosporin use
UTI’s, resp infections, surgical proph.
GAS pathology
Exotoxins, C5a peptidase, M protein, hyaluronidase
H pylori patholgoy
VacA erodes epithelium
Plasmodium sp. treatment
Fluoroquinolones, doxycycline
Legionella Pneumophilia diagnosis
Gram neg coccobacilli, test for urine antigen
H pylori disease
Gastric adenocarcinoma
Macrolides names and effect
Azithromycin (Z-pak), Clarithromycin, clindamycin, erythromycin, bacteriostatic (protein trans)
B. cereus treatment
rehydration
T. pallidum treatment
Penicillin G, doxycyline in allergic
Clostridium perfringens treatment
Rehydration
Neisseria gonorrhea treatment
Single dose cefriaxone, azithro for chlamydia
PSeudomonas aeruginosa treatement
Test for sensitivity
GBS diagnosis
catalase negative, beta hemolytic, bacitracin resistant
Borellia burgdorferi treatment
Doxycycline
B fragilis disease
abcesses
Plasmodium sp. pathology
Mosquitos, falciparum is 95% of deaths, life cycle step 1: sporozoites enter the liver, step 2: merozots invade RBC’s (Ovale and Vivax have dormant stages), erythrocytic phase - infected RBC’s become deformed, anemia and jaudice
EAEC disease
Watery diarrhea
Mycobacterium leprae treatment
Rifampicin, dapsone, clofazimine
Rickettsi r. pathology
Vasc endothelial cells, cell cell spread using actin, lekage of RBC
Plasmodium sp. disease
High fever, chills, rigor, anemia, spiking periodic fevers
G. lamblia disease
Steatorrhea, foul smelling
Borellia burgdorferi pathology
Tick blood meal, OspC, Salp15 evasion, tick, mouse, lizards
Pseudomonas aeruginosa diseases
Pulmonary infections, hot tub folliculitis, otitis externa, corneal infection
B fragilis treatement
metronidazole, oral vanco
Step pneumonia pathology
CbpA for capsule mediated inhibition of clearance, often after viral infection
Entamoeba histolytica disease
cysts infectious, flask shaped ulcers, colon lesions, bloody stool
GBS diseasse
Maternal fetal, GI and urogenital, UTI, sepsis, meningitis, pneumonia
Tetracyclin side effects
discolored teeth, GI upset, phototoxic dermatitis, dont use in pregnant or children