Exam II Organogenetic Period Part II Flashcards
Upper limbs appear day ____, lower limbs appear day ____.
26, 28
Limb development not complete until week ____.
8
Differentiation begins in the ____ of the lateral somatic mesoderm.
Mesenchyme
Each limb bud is made up of a ____ core covered by ectoderm.
Mesenchymal
The end of each limb bud is covered by a thickening of the ectoderm called the ____.
Apical ectoderm ridge
The apical ectodermal ridge produces signaling agents that control ____ development.
Limb
Limb buds first appear on the ____ portion of the body walls.
Anterior
Upper limb buds develop ____ lower (caudal) cervical somites.
Opposite
Limb buds begin slightly ____ than their final location due to cranial development.
Lower
Lower limb buds develop ____ the lumbar and upper sacral somites.
Opposite
Initially, upper and lower limb bud development is ____ but as development progresses, each become more specialized.
The same
Dermatome placement along limb bud has lower cervical ____.
Most distally.
Blood vessels and cartilage bone model develop from mesenchyme adjacent to the ____.
Apical ectodermal ridge
The apical ectodermal ridges ____ to form hand and foot plates.
Flatten
Week ____, the hands precede the feet by a couple of days.
5
The mesenchymal tissue in the hand and foot plates ____ to form digital rays.
Condense
Digital rays are the primordium of fingers and toes and are present by the end of week ____.
6
The apical ectodermal ridge ____ development of bones and the end of each digital rays.
Induces
Phalanges form from the apical ectodermal ridge with loose ____ tissue between the phalanges.
Mesenchymal
By the ____ week, the mesenchymal tissue between the phalanges deteriorates leaving individual fingers.
8th
Development of the appendicular skeleton coincides with mesenchymal tissue ____ to form chondrification centers beginning week 5.
Aggregation
A ____ skeleton in each limb is formed by the end of week 6.
Cartilaginous
____ of the long bones begins in week 7.
Osteogenesis (ossification)
The ____ is the first long bone to undergo osteogenesis.
Femur
Ossification centers are ____ in all of the long bones by week 12.
Present
Spinal nerves begin forming the ____ and ____ plexuses and enter the limbs during week 5.
Brachial and lumbosacral
Brachial and lumbosacral plexuses form ____ nerves.
Peripheral
____ nerves are the first to form in limb innervation.
Motor
Sensory nerves follow the motor nerves using them as ____.
Guides
Neural crest cells differentiate forming ____ cells.
Schwann cells
Neurolemma and myelin sheath are formed as part of the ____ cells.
Schwann
Dermatome patterns of ____ nerves form during innervation of the limbs phase.
Cutaneous
Hands ____ feet in innervation of the limbs.
Precede
Dermatomes are the principle foundation of manual muscle testing and fall under ____ law.
Hilton’s
Dermatomes are an area of skin originating from an individual ____.
Somite
Dermatomes are innervated by ____ spinal nerves.
Specific, individual
Development of the respiratory system begins week 4 and continues into the later part of the ____ period.
Fetal
Development of the respiratory system leads to formation of the following organs:
Larynx, trachea, bronchi, and lungs
The respiratory system differentiates from the cranial portion of the foregut below the ____ pharyngeal arch.
4th
During respiratory development, formation of the laryngotracheal ____ occurs on the cranial end of the foregut below the 4th pharyngeal pouch.
Groove
The ____ lining of the laryngotracheal groove gives rise to the epithelium and glands of the larynx, trachea, bronchi, and pulmonary epithelium.
Endodermal
During respiratory development connective tissue, cartilage, and smooth muscle develop from the ____ mesoderm surrounding the foregut.
Splanchnic
A pouch of laryngotracheal diverticula forms by the end of week ____ in respiratory development.
4
Laryngotracheal diverticula forms from invagination of the laryngotracheal ____.
Groove
As the laryngotracheal diverticulum grows, its ____ end enlarges to form a globular respiratory bud.
Distal
The globular respiratory bud is the beginning of the ____ and ____.
Lung and bronchi
The laryngotracheal diverticulum ____ from the primordial pharynx.
Separates