Exam 5: Part 2 Flashcards
IgG
Y shaped, gives immunity to fetus during pregnancy
IgD
- Y shaped, B cell receptor
Cephalosporin
Beta lactam ring bonded to Nitrogen
Carbapenem
Beta lactam bonded to Carbon
Aminoglycosides
Target 30s ribosomal subunit, preventing proofreading
Tetracyclines
Block 30S ribosomal subunit, block association of aminoacyl tRNA with A site of ribosome, preventing protein synthesis
Macrolides
Block 50s ribosomal subunit’s peptidyl transferase, slowing protein synthesis
Lincosamides
Target 50s’ 23S portion, causing dissociation of of small peptide chains, stopping protein synthesis
How is selective toxicity achieved?
Targeting organelles unique to bacteia
Artemisnin
Attacks many proteins in Plasmodium falciparum
Chloroquine
Damages membrane of parasite causing malaria ( Entamoeba histolytica)
Acyclovir treats ________
HIV
How do WBCs know where to go in sites of infection?
Release of chemokines