Exam 3 Flashcards
Lispro is an insulin analogue produced by recombinant DNA technology. Which of the following statements about this form of insulin is NOT true?
A. Optimal time of preprandial injection is 15 minutes.
B. Duration of action is increased when the dose is increased.
C. It is compatible with neutral protamine Hagedorn insulin.
D. It has no pronounced peak.
B. Duration of action is increased when the dose is increased.
The action of “gliptins” is different from other antidiabetic agents because they:
A. Have a low risk for hypoglycemia
B. Are not associated with weight gain
C. Close ATP-dependent potassium channels in the beta cell
D. Act on the incretin system to indirectly increase insulin production
D. Act on the incretin system to indirectly increase insulin production
After starting a patient with Grave’s disease on an antithyroid agent such as methimazole, patient monitoring includes TSH and free T4 every:
1 to 2 weeks
3 to 4 weeks
2 to 3 months
6 to 9 months
3 to 4 weeks
Type 2 diabetes is a complex disorder involving:
A. absence of insulin production by beta cells
B. A suboptimal response of insulin-sensitive tissues in the liver
C. Increased levels of glucagon-like peptide in postprandial period
D. Too much fat uptake in intestine
A suboptimal response of insulin-sensitive tissues in the liver
Prevention of conversion from prediabetes to diabetes in young children must take highest priority and should focus on:
A. Aggressive dietary manipulation to prevent obesity
B. Fostering LDL levels less than 100 mg/dl and total cholesterol less than 170 mg/dl to prevent cardiovascular disease
C. Maintaining a blood pressure that is less than 80% based on weight and height to prevent hypertension
D. All of the above
B. Fostering LDL levels less than 100 mg/dl and total cholesterol less than 170 mg/dl to prevent cardiovascular disease
Nonselective beta blockers and alcohol create serious drug interactions with insulin because they:
A. Increase blood glucose levels
B. Produce unexplained diaphoresis
C. Interfere with the ability of the body to metabolize glucose
D. Mask the signs and symptoms of altered glucose levels
Mask the signs and symptoms of altered glucose levels
Metformin is a primary choice of drug to treat hyperglycemia in type 2 diabetes because it:
Substitutes for insulin usually secreted by the pancreas
Decreases glycogenolysis by the liver
Increases the release of insulin from beta cells
Decreases peripheral glucose utilization
Decreases glycogenolysis by the liver
Allison is an 18-year-old college student with type 1 diabetes. She is on NPH twice daily and Novolog before meals. She usually walks for 40 minutes each evening as part of her exercise regimen. She is beginning a 30-minute swimming class three times a week at 1 p.m. What is important for her to do with this change in routine?
Delay eating the midday meal until after the swimming class.
Increase the morning dose of NPH insulin on days of the swimming class.
Adjust the morning insulin injection so that the peak occurs while swimming.
Check glucose level before, during, and after swimming.
Check glucose level before, during, and after swimming.
All of the following are options for insulin injections when each dose is close to 100 units except:
1.
Split dosing
2.
Move to insulin pen use
3.
Change to U500 insulin
4.
Stop injectable insulin and change to oral methods only
4.
Stop injectable insulin and change to oral methods only
When is metformin typically initiated for glucose metabolism issues?
1. Only after the HgA1C is greater than 8.0
2. When the patient is diagnosed with prediabetes
3. When metabolic syndrome ensues
4. When true diabetes mellitus (DM_ is diagnosed
- When the patient is diagnosed with prediabetes
The American Diabetic Association has recommended which of the following tests for ongoing management of diabetes?
Fasting blood glucose
HbA1C
Thyroid function tests
Electrocardiograms
HbA1C
What is the desired ratio of T3 to T4 drug levels in newly diagnosed endocrine patients?
A. 99% of T3 and the rest is T4 to get rapid resolution.
B. Most needs to be T4 to mimic natural ratios of hormone.
C. The ratio is unimportant.
D. The mix needs to be 50-50 at first.
Most needs to be T4 to mimic natural ratios of hormone.
When methimazole is started for hyperthyroidism it may take ________ to see a total reversal of hyperthyroid symptoms.
2 to 4 weeks
1 to 2 months
3 to 4 months
6 to 12 months
6 to 12 months
Diabetic autonomic neuropathy (DAN) is the earliest and most common complication of diabetes. Symptoms associated with DAN include:
Resting tachycardia, exercise intolerance, and orthostatic hypotension
Gastroparesis, cold intolerance, and moist skin
Hyperglycemia, erectile dysfunction, and deficiency of free fatty acids
Pain, loss of sensation, and muscle weakness
Resting tachycardia, exercise intolerance, and orthostatic hypotension
Goals when treating hypothyroidism with thyroid replacement include:
A. Normal TSH and free T4 levels
B. Resolution of fatigue
C. Weight loss to baseline
D. All of the above
All of the above
All diabetic patients with hyperlipidemia should be treated with:
HMG-CoA reductase inhibitors
Fibric acid derivatives
Nicotinic acid
Colestipol
HMG-CoA reductase inhibitors
Control targets for patients with diabetes include:
HbA1C between 7 and 8
Fasting blood glucose levels between 100 and 120 mg/dl
Blood pressure less than 130/80 mm Hg
LDL lipids less than 130 mg/dl
Blood pressure less than 130/80 mm Hg
Allison is an 18-year-old college student with type 1 diabetes. Allison’s pre-meal BG at 11:30 a.m. is 130. She eats an apple and has a sugar-free soft drink. At 1 p.m. before swimming her BG is 80. What should she do?
Proceed with the swimming class.
Recheck her BG immediately.
Eat a granola bar or other snack with CHO.
Take an additional dose of insulin.
Eat a granola bar or other snack with CHO.
Thyroid medullary cancer risk has been linked with:
1.
Chronic sulfonylurea use
2.
Later addition of basal insulin to oral therapy
3.
GLP-1 therapies
4.
SGLT-2 medication
3.
GLP-1 therapies
Long-term injection site skin changes are called:
1.
Lipodystrophy
2.
Tuberous sclerosis
3.
Telangiectasia
4.
Medication caveronosa
1.
Lipodystrophy
A patient is started on paroxetine (Paxil), an SSRI, for depression. Education regarding antidepressants includes:
SSRIs may take two to six weeks before she will have maximum drug effects.
(B Red-green color blindness may occur and should be reported.
(C) if she experiences dry mouth or a heart rate greater than 80, she should stop taking the drug immediately.
(D She should eat lots of food high in fiber to prevent constipation.
SSRIs may take two to six weeks before she will have maximum drug effects.
A patient fractured his ankle in two places and is asking for medication for his pain. The appropriate first-line medication would be:
Ibuprofen (Advil)
(B Acetaminophen with hydrocodone (Vicodin)
(C) Oxycodone (Oxycontin)
(b) Oral morphine (Roxanol)
(B Acetaminophen with hydrocodone (Vicodin)
An adult is taking lithium for bipolar disorder. They should be taught to:
(A) Take lithium with food
(B) Eat a diet with consistent levels of salt (sodium)
C Drink at least two quarts of water if they are in a hot environment
(D Monitor blood glucose levels
(B) Eat a diet with consistent levels of salt (sodium)
Baseline assessment prior to starting a child on stimulants for ADHD includes
(A Height, weight, and blood pressure
(B Fasting glucose
C) Liver enzymes
Height, weight, and blood pressure
Nonpharmacologic therapy for tension headaches includes:
(A) Biofeedback
B) Stress management
(C) Massage therapy
D) All of the above
All of the above
An 8-year-old male has attention deficit disorder (ADD) and is prescribe methylphenidate (Ritalin). He and his parents should be educated about side effects of methylphenidate, which are:
(A) Slurred speech and insomni
B Bradycardia and con fusion
(C Dizziness and orthostatic hypotensio
(D Insomnia and decreased appetite
Insomnia and decreased appetite
Patients who are prescribed olanzapine (Zyprexa) should be monitored for:
A) Insor mnia
(B Weight gain
C Hypertension
(D Galactorrhea
Weight gain
Prior to starting antidepressants, patients should have laboratory testing to rule out:
Hypothyroidism
(B Anemia
(C Diabetes mellitus
(D) Low estrogen levels
Hypothyroidism
Tricyclic antidepressants should be prescribed cautiously in patients with:
Eczema
(B Asthma
(C) Diabetes
(D Heart disease
Heart disease
An appropriate drug for the treatment of depression with anxiety would be:
Alprazolam (Xanax)
(B Escitalopram (Lexapro)
(c) Buspirone (Buspar)
D) Amitriptyline (Elavil)
Escitalopram Lexapro
A 66-year-old male was prescribed phenelzine (Nardil) while in an acute psychiatric unit for recalcitrant depression. The nurse practitioner (NP) managing his primary health care needs to understand the following regarding phenelzine and other monoamine oxidase inhibitors (MAOIs):
(A) He should not be prescribed any serotonergic drug such as sumatriptan (Imitrex).
(B MAOIs interact with many common foods, including yogurt, sour cream, and soy sauce.
C) Symptoms of hypertensive crisis (headache, tachycardia, sweating) require immediate treatment.
D) All of the above
All of the above
Scott’s seizures are well controlled on topiramate and he wants to start playing baseball. Education for Scott regarding his topiramate includes:
(A)
He should not play sports due to the risk of increased seizures
(B He should monitor his temperature and ability to sweat in the heat while playing
(C Reminding him that he may need higher doses of topiramate when exercising
(D) Encouraging him to use sunscreen due to photosensitivity from topiramate
(B He should monitor his temperature and ability to sweat in the heat while playing
Question 13
A first-line drug for abortive therapy in simple migraine is:
(A) Sumatriptan (Imitrex)
(B) Naproxen (Aleve)
(C Butorphanol nasal spray (Stadol NS)
D Butolbital and acetaminophen Fiorecet
B) Naproxen Aleve
Migraines in pregnancy may be safely treated with:
(A) Acetaminophen with codeine (Tylenol #3)
(B) Sumatriptan (Imitrex)
(C Ergotamine tablets (Ergostat)
(D Dihydroergotamine (DHE)
A acetaminophen with codeine Tylenol 3
A patient has been diagnosed with cluster headaches. Appropriate acute therapy would be:
(A Butalbital and aspirin (Fiorinal)
(B) Intramuscular (IM) meperidine (Demerol)
(C Oxygen 100% for 15 to 30 minutes
(D) Indomethacin (Indocin)
Oxygen 100% for 15 to 30 minutes
Carbamazepine has a black box warning due to life threatening:
Renal toxicity, leading to renal failure
(B Hepatotoxicity, leading to liver failure
( Dermatologic reaction, including Steven’s Johnson and toxic epidermal necrolysis
(D) Cardiac effects, including supraventricular tachycardia
Dermatologic reaction, including Steven’s Johnson and toxic epidermal necrolysis